Results 241 to 250 of about 5,194,805 (386)

An analysis by gel electrophoresis of Q-beta-RNA complexes formed during the latent period of an in vitro synthesis.

, 1967
D. H. L. Bishop, J. Russell Claybrook, Norman R. Pace, S. Spiegelman   +3 more
openalex   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Active RNA: RNA enzymes in RNA splicing and processing [PDF]

Bioscience Reports, 1984
openaire   +2 more sources

RNA binding and coacervation promote preservation of peptide form and function across the heterochiral-homochiral divide. [PDF]

Protein Sci
Seal M, Edelstein I, Scolnik Y, Weil-Ktorza O, Metanis N, Levy Y, Longo LM, Goldfarb D.   +7 more
europepmc   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Identification and structural insights into RNA motifs targeted by a CAG repeat DNA-binding small molecule. [PDF]

Chem Sci
Chen Q, Fujiwara A, Nakatani K, Kawai G, Murata A.   +4 more
europepmc   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

DNA, RNA融解曲線の自記記録装置

, 1966
Sadato Yabuki, Akiyoshi Wada
openalex   +2 more sources

A. Rna-Tas: Tibeto-Mongolica: the Tibetan loanwords of Monguor and the development of the archaic Tibetan dialects. (Indo-Iranian Monographs, Vol. VII.) 232 pp. The Hague, etc.: Mouton and Co., 1966. Guilders 28. [PDF]

, 1967
K. K. Sprigg
openalex   +1 more source