Results 311 to 320 of about 5,194,805 (386)

Epitranscriptomic alterations induced by environmental toxins: implications for RNA modifications and disease. [PDF]

Genes Environ
Alum EU, Ejemot-Nwadiaro RI, Basajja M, Uti DE, Ugwu OP, Aja PM.   +5 more
europepmc   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Systemic mRNA aggregates elicit immunologic reprogramming that unlocks anti-cancer immunity. [PDF]

Hum Vaccin Immunother
Mendez-Gomez HR, Ligon JA, Ghiaseddin AP, Sayour EJ.   +3 more
europepmc   +1 more source

INHIBITION OF DNA-DEPENDENT RNA SYNTHESIS BY RIFAMYCINS

, 1968
HAMAO UMEZAWA, Satoshi Mizuno, Hisaji Yamazaki, Kazuo Nitta   +3 more
openalex   +2 more sources

Osmotic pressure‐induced calcium response states

FEBS Open Bio, EarlyView.
Acute hypotonic stress triggers distinct calcium response patterns in HEK293T cells. These signals originate from the endoplasmic reticulum via RyR2 and propagate to neighboring cells through gap junctions. This result highlights a novel calcium‐dependent mechanism underlying the intracellular and intercellular response to osmotic pressure.
Zidan Gao, Keiji Naruse, Masatoshi Morimatsu   +2 more
wiley   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

RELEASE OF TRANSFER RNA DURING PEPTIDE CHAIN ELONGATION

, 1969
Jean Lucas‐Lenard, Anne‐Lise Haenni
openalex   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source