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RNA-binding proteins in RNA interference

Molecular Biology, 2006
Short RNAs (21–27 nt) silence genes that contain homologous nucleotide sequences; this is known as RNA silencing. This review considers the generation of short RNAs from their precursors: double-stranded RNAs, capable of inducing RNA interference, and hairpin RNAs, whose processing yields microRNAs, as well as the properties of RNA-binding domains that
R. N. Kotelnikov   +3 more
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Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

Biochemical Society Transactions, 2008
PTB (polypyrimidine-tract-binding protein) is a ubiquitous RNA-binding protein. It was originally identified as a protein with a role in splicing but it is now known to function in a large number of diverse cellular processes including polyadenylation, mRNA stability and translation initiation.
Kirsty, Sawicka   +3 more
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Single stranded RNA binding proteins

Current Opinion in Structural Biology, 2000
Our knowledge of protein interactions with RNA molecules has been, so far, largely restricted to cases in which the RNA itself is folded into a secondary and/or tertiary structure stabilised by intramolecular base pairing and stacking. Until recently, only limited structural information has been available about protein interactions with single-stranded
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RNA-binding proteins tamed

Nature Structural & Molecular Biology, 1998
Novel RNA-binding proteins with customized specificities can be isolated by genetic selection from combinatorial libraries. Such proteins have great potential as agents for targeted manipulation of gene expression.
Ite A. Laird-Offringa, Joel G. Belasco
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The RNA-binding proteins

2015
This chapter details how RNA-binding proteins package RNA, protect RNA, organize RNA, and prepare RNA for post-transcriptional processes. It describes different kinds of RNA-binding and auxiliary domains that enable RNA-binding proteins to bind RNA in a versatile way.
David Elliott, Michael Ladomery
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RNA binding proteins

2022
Stephen Neidle, Mark Sanderson
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RNA-Binding Proteins in Cancer: Old Players and New Actors.

Trends in Cancer, 2017
B. Pereira, M. Billaud, R. Almeida
semanticscholar   +1 more source

Structures of RNA-binding proteins

Quarterly Reviews of Biophysics, 1997
J G, Arnez, J, Cavarelli
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