Results 261 to 270 of about 1,056,288 (288)

Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development

Advanced Biology, EarlyView.
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng, Wangyu Luo, Yichen Yao, Lichieh Lin, Laiting Chan, Jiarui Lu, Zijing Huang, Jingyi Feng, Le Zhao, Xiaolei Zhang, Liu Yang   +10 more
wiley   +1 more source

Author Correction: A cost-effective RNA extraction and RT-qPCR approach to detect California serogroup viruses from pooled mosquito samples. [PDF]

Sci Rep
Avramov M, Gallo V, Gross A, Lapen DR, Ludwig A, Cullingham CI.   +5 more
europepmc   +1 more source

Exploring the potential of a saliva-based, RNA-extraction-free PCR test for the multiplexed detection of key respiratory pathogens

, 2023
Allicock OM, Lin T, Fajardo KT, Yolda-Carr D, Hislop MS, Wang J, Zuniga D, Platt W, Tuohy B, Wyllie AL.   +9 more
europepmc   +1 more source

TRIzol-Based RNA Extraction in Adult Zebrafish v1 [PDF]

Francisco Fuentealba Villarroel, Gabriela Otarão Rosa, Stéfani Malet Portela, Sara Hartke, Matheus Gallas Lopes, Ana P Herrmann, Ângelo Piato   +6 more
openalex   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

FOXP3 Polymorphism and Upregulation of the CXCL12‐CXCR4‐SNAIL Axis with High Infiltration of M2TAM by STAT3/NFKB Pathways Influence the Survival of Cervical Cancer Patients

Advanced Biology, EarlyView.
This study highlights how cervical carcinoma progression is shaped by immune–tumor interactions within the TME. M2‐TAM infiltration, regulated through STAT3/NF‐κB and linked to CXCL12–CXCR4, promotes immune suppression, angiogenesis, and poor survival.
George A. Lira, Fábio M. de Azevedo, Ingrid G. S. Lins, Janaína C. O. Crispim, Giovanna A. Lira, Rômulo S. Cavalcante, Ricardo Cobucci, Carolina O. Mendes‐Aguiar, Rafaela Torres Dantas Da Silva, Vinícius E. da Silva, Ryan C. Q. Aquino, Raimundo F. Araújo Júnior   +11 more
wiley   +1 more source

Cross comparison of alternative diagnostic protocols including substitution to the clinical sample, RNA extraction method and nucleic acid amplification technology for COVID-19 diagnosis. [PDF]

Front Mol Biosci
Segura-Ulate I, Apú N, Cortés B, Querol-Audi J, Zaldívar Y, Ortega CA, Flores-Mora F, Gatica-Arias A, Madrigal-Redondo G.   +8 more
europepmc   +1 more source

Performance Evaluation of the Maxwell 16 System for Extraction of Influenza Virus RNA from Diverse Samples

, 2012
Hongbo Liu, Yan Gan, Bo Yang, Hui Weng, Chunmei Huang, Daofeng Yang, Ping Lei, Guanxin Shen   +7 more
openalex   +2 more sources

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source

An Optimized and Cost-Effective RNA Extraction Method for Secondary Metabolite-Enriched Tissues of Norway Spruce (Picea abies). [PDF]

Plants (Basel)
Singh VV, Naseer A, Sellamuthu G, Jakuš R.   +3 more
europepmc   +1 more source