Results 171 to 180 of about 115,962 (247)

The Role of N6-Methyladenosine in Mitochondrial Dysfunction and Pathology. [PDF]

Int J Mol Sci
Yan W, Saqirile, Li K, Li K, Wang C.
europepmc   +1 more source

Decoding RNA–Protein Interactions: Methodological Advances and Emerging Challenges

Advanced Genetics, EarlyView.
This review provides a comprehensive comparison of RNA‐ and protein‐centric methodologies for investigating RNA–protein interactions, emphasizing their respective advantages, limitations, and suitable applications. It highlights recent technological innovations, outlines strategic method selection criteria, and addresses key challenges.
Wenkai Yi, Jian Yan
wiley   +1 more source

Exploring the Anti-Leukemic Effect of the Synthetic Retinoid ST1926 on Malignant T Cells: A Comprehensive Proteomics Approach. [PDF]

Int J Mol Sci
Goli M, Sandilya V, Ghandour B, Hajj HE, Kobeissy F, Darwiche N, Mechref Y.   +6 more
europepmc   +1 more source

Potent inhibitors of the human RNA ligase Rlig1 highlights its role in RNA integrity maintenance under oxidative cellular stress. [PDF]

Chem Sci
Schlor LA, Peußner M, Müller S, Marx A.   +3 more
europepmc   +1 more source

DNA Ligase I Circularises Potato Spindle Tuber Viroid RNA in a Biomolecular Condensate. [PDF]

Mol Plant Pathol
Wang Y, Ma J, Hao J, Liu B, Wang Y.
europepmc   +1 more source

E3 Siah ubiquitin ligase regulates dichotomous spermatogenesis in Sitotroga cerealella. [PDF]

Front Cell Dev Biol
Shah S, Shi CM, Elgizawy KK, Yan WH, Wu G, Wang XP, Yang FL.   +6 more
europepmc   +1 more source

Recent Advancements in Microfluidic Biosensors for Clinical Applications

iLABMED, EarlyView.
The combination of low‐consumption microfluidic chips and high‐sensitivity biosensors enables rapid and accurate detection of complex target analytes. This integrated system holds significant potential for applications in disease diagnosis, health monitoring, and treatment management.
Haiyan Wang, Wenjuan Wu
wiley   +1 more source

Depletion of WWP1 Increases Adrb3 Expression and Lipolysis in White Adipose Tissue of Obese Mice. [PDF]

Int J Mol Sci
Nozaki Y, Ose Y, Ohmori C, Mizunoe Y, Kobayashi M, Saitoh A, Higami Y.   +6 more
europepmc   +1 more source

Construction of Reporter Phage T4::Nluc and Its Application in the Detection of Escherichia coli in Urinary Tract Infections

iLABMED, EarlyView.
A reporter phage T4::Nluc was constructed using the CRISPR/Cas9 system combined with homologous recombination and was applied for the detection of clinical Escherichia coli in urinary tract infections (UTIs). T4::Nluc exhibited superior sensitivity and specificity, and had a short detection time, making it a powerful tool for diagnosing UTIs.
Zhiyun Hao, Minwei Li, Qiang Zhao, Liye Wang, Ting Liu, Chi Wang, Chengbin Wang   +6 more
wiley   +1 more source

PROTAC Technology as a New Tool for Modern Pharmacotherapy. [PDF]

Molecules
Kubryń N, Fijałkowski Ł, Nowaczyk J, Jamil A, Nowaczyk A.   +4 more
europepmc   +1 more source