Results 201 to 210 of about 4,574 (248)

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

RNA localization and transport

Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms, 2018
RNA localization serves numerous purposes from controlling development and differentiation to supporting the physiological activities of cells and organisms. After a brief introduction into the history of the study of mRNA localization I will focus on animal systems, describing in which cellular compartments and in which cell types mRNA localization ...
Beat Suter
exaly   +5 more sources

RNA localization

The FASEB Journal, 1999
L D, Etkin, H D, Lipshitz
openaire   +3 more sources

A novel role for Celf1 in vegetal RNA localization during Xenopus oogenesis

Developmental Biology, 2015
The localization of certain mRNAs to the vegetal cortex of Xenopus oocytes is of crucial importance for germ cell development and early embryonic patterning. Vegetal RNA localization is mediated by cis-acting RNA localization elements (LE).
Maike Clausen, Tomáš Pieler
exaly   +2 more sources

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Localized RNAs and their functions

BioEssays, 1993
AbstractThe eukaryotic cell is partitioned by membranes into spatially and functionally discrete subcellular organelles. In addition, the cytoplasm itself is partitioned into discrete subregions that carry out specific functions. Such compartmentation can be achieved by localizing proteins and RNAs to different subcellular regions.
D, Ding, H D, Lipshitz
openaire   +2 more sources

Local RNA folding revisited

Journal of Bioinformatics and Computational Biology, 2023
Most of the functional RNA elements located within large transcripts are local. Local folding therefore serves a practically useful approximation to global structure prediction. Due to the sensitivity of RNA secondary structure prediction to the exact definition of sequence ends, accuracy can be increased by averaging local structure predictions over ...
Maria Waldl, Thomas Spicher, Ronny Lorenz, Irene K. Beckmann, Ivo L. Hofacker, Sarah von Löhneysen, Peter F. Stadler   +6 more
openaire   +2 more sources

Locality and Gaps in RNA Comparison

Journal of Computational Biology, 2007
Locality is an important and well-studied notion in comparative analysis of biological sequences. Similarly, taking into account affine gap penalties when calculating biological sequence alignments is a well-accepted technique for obtaining better alignments.
Rolf Backofen, Shihyen Chen, Danny Hermelin, Gad M. Landau, Mikhail A. Roytberg, Oren Weimann, Kaizhong Zhang   +6 more
openaire   +3 more sources

RNA localization inXenopusoocytes

Seminars in Cell & Developmental Biology, 1997
The transport and localization of mRNAs within Xenopus oocytes contributes to an asymmetry that determines axis formation in the embryo. Several mRNAs become localized along the animal-vegetal axis. The mitochondrial cloud, a specialized cytoplasmic compartment which contributes to the formation of germ plasm, and the endoplasmic reticulum play ...
, Schnapp, , Arn, , Deshler, , Highett
openaire   +2 more sources

Localized control of oxidized RNA

Journal of Cell Science, 2015
The oxidation of biological molecules by reactive oxygen species can render them inactive or toxic. This includes the oxidation of RNA, which appears to underlie detrimental effects of oxidative stress, aging, and certain neurodegenerative diseases. Here we investigate the management of oxidized RNA in the chloroplast of the green alga Chlamydomonas ...
Yu, Zhan, James S, Dhaliwal, Pauline, Adjibade, James, Uniacke, Rachid, Mazroui, William, Zerges   +5 more
openaire   +2 more sources