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Deregulation of m6A-RNA methylation impairs adaptive hypertrophic response and drives maladaptation via mTORC1-S6K1-hyperactivation and autophagy impairment. [PDF]

open access: yesCell Commun Signal
Annamalai K   +17 more
europepmc   +1 more source
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RNA nucleotide methylation

WIREs RNA, 2011
AbstractMethylation of RNA occurs at a variety of atoms, nucleotides, sequences and tertiary structures. Strongly related to other posttranscriptional modifications, methylation of different RNA species includes tRNA, rRNA, mRNA, tmRNA, snRNA, snoRNA, miRNA, and viral RNA.
Yuri, Motorin, Mark, Helm
openaire   +2 more sources

RNA methylations in human cancers

Seminars in Cancer Biology, 2021
RNA methylations, as the prevalent post-transcriptional modifications, are critical in regulating various biological processes, such as RNA transcription, splicing, structure, stability, and translation. Its dysregulation is closely related to the occurrence of human malignancies.
Xiao, Han   +4 more
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RNA-directed DNA methylation

Journal of Cell Science, 2004
Double-stranded RNAs (dsRNAs) and their `diced' small RNA products can guide key developmental and defense mechanisms in eukaryotes. Some RNA-directed mechanisms act at a post-transcriptional level to degrade target messenger RNAs. However, dsRNA-derived species can also direct changes in the chromatin structure of DNA regions with which they share ...
Mathieu, Olivier, Bender, Judith
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