Results 241 to 250 of about 708,746 (292)

Direct single-molecule detection and super-resolution imaging with a low-cost portable smartphone-based microscope. [PDF]

Nat Commun
Loretan M, Barella M, Fuchs N, Kocabey S, Kołątaj K, Stefani FD, Acuna GP.   +6 more
europepmc   +1 more source

Biological Nanoscaffolds from Hierarchical Construction to Applications. [PDF]

Molecules
Zhang Y, Shi H, Li Y, Shen Y, Wang T, Liu J.   +5 more
europepmc   +1 more source

Quantification of disease-associated RNA tandem repeats by nanopore sensing

Patiño-Guillén G, Pešović J, Panić M, Earle M, Ninković A, Petrușca S, Savić-Pavićević D, Keyser U, Bošković F.   +8 more
europepmc   +1 more source

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RNA Nanostructure Molecular Imaging

Methods in Molecular Biology, 2020
Atomic force and transmission electron microscopies (AFM/TEM) are powerful tools to analyze RNA-based nanostructures. While cryo-TEM analysis allows the determination of near-atomic resolution structures of large RNA complexes, this chapter intends to present how RNA nanostructures can be analyzed at room temperature on surfaces.
Olivier Pietrement, Véronique Arluison, Christophe Lavelle   +2 more
exaly   +4 more sources

Role of Dynamics in RNA Nanostructure Design

2013
One of the goals of RNA-based nanotechnology is the development of smart molecules capable of disrupting oncogenic and disease molecular pathways in a selective way. RNA is well suited to combining structural scaffolds and active agents made out of the same building material.

exaly   +2 more sources

RNA nanostructure transformation into DNA ones

Nano Research, 2022
Jiazhen Lyu
exaly   +2 more sources

RNA Nanostructures: From Structure to Function

Bioconjugate Chemistry, 2022
Nucleic-acid nanostructures, which have been designed and constructed with atomic precision, have been used as scaffolds for different molecules and proteins, as nanomachines, as computational components, and more. In particular, RNA has garnered tremendous interest as a building block for the self-assembly of sophisticated and functional ...
Ofer I. Wilner, Doron Yesodi, Yossi Weizmann   +2 more
openaire   +2 more sources

DNA nanostructures directed by RNA clamps

Nanoscale, 2021
DNA chains can be folded rationally by using DNA staples, and the programmed structures are of great potential in nanomaterial studies.
Jiazhen Lyu, Mei Yang, Chong Zhang, Yongbo Luo, Tong Qin, Zhaoming Su, Zhen Huang   +6 more
openaire   +2 more sources

Assessment of Intracellular Compartmentalization of RNA Nanostructures

2023
Nucleic acid nanoparticles (NANPs) are extensively investigated as diagnostic and therapeutic tools. These innovative particles can be composed of RNA, DNA, and/or modified nucleic acids. Due to the regulatory role of nucleic acids in the cellular system, NANPs have the ability to identify target molecules and regulate expression of genes in disease ...
Yasmine, Radwan, Kirill A, Afonin, M Brittany, Johnson   +2 more
openaire   +2 more sources

Branched RNA nanostructures for RNA interference

Chemical Communications, 2011
Branched RNAs with three- or four-way junctions were designed by assembling single-stranded RNA for RNA interference. Human Dicer transformed branched RNAs into about 20 base pairs of double-stranded RNA, which is a standard siRNA species. Our tetramer design provides a potent silencing effect over a period of 5 days.
Yuko, Nakashima, Hiroshi, Abe, Naoko, Abe, Kyoko, Aikawa, Yoshihiro, Ito   +4 more
openaire   +2 more sources