Reinitiation of RNA Synthesis on Transcription of Chromatin DNA by Escherichia coli RNA Polymerase [PDF]
Margaret Eleanor Morris, Hannah J. Gould
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Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee+9 more
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Evolutionary and Structural Insights into the RNA Polymerase I A34 Protein Family: A Focus on Intrinsic Disorder and Phase Separation. [PDF]
Knutson BA, Rothblum LI.
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Defining the Influence of the A12.2 Subunit on Transcription Elongation and Termination by RNA Polymerase I In Vivo. [PDF]
Clarke AM+4 more
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DNA‐dependent RNA polymerase from the thermophilic bacterium Thermus aquaticus
Gillian M. Air, J. Ieuan Harris
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The Synthesis In Vitro of RNA Polymerase Subunits of Escherichia coli [PDF]
Stuart Austin, Duncan J. McGeoch
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Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla+16 more
wiley +1 more source
RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells. [PDF]
Otto C+15 more
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