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Current Opinion in Cell Biology, 1992
Significant progress has been made over the last year in our understanding of the roles that RNA-binding proteins play in pre-mRNA splicing, the components of the spliceosome and how these components relate to the mechanism of splicing. Of particular importance has been the sequence analysis of the first mammalian splicing factors and structural ...
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Significant progress has been made over the last year in our understanding of the roles that RNA-binding proteins play in pre-mRNA splicing, the components of the spliceosome and how these components relate to the mechanism of splicing. Of particular importance has been the sequence analysis of the first mammalian splicing factors and structural ...
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RNA processing: New mutants that affect endonucleolytic processing of RNA
Biochemical and Biophysical Research Communications, 1983A strain of Escherichia coli carrying the rne-3071 mutation that affects the RNA processing enzyme ribonuclease E, was mutagenized, and double mutants deficient in RNA processing were isolated. The isolation was based on the appearance of a particular RNA precursor molecule upon infection of an rne mutant with a specific bacteriophage T4 deletion ...
A, Miczak +3 more
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2021
This chapter explores RNA processing events, which are points for regulation and quality control, and are sources of diversity. Many RNA processing reactions are directed by RNA components. Transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs) are processed out of longer precursor transcripts, and the nucleotides are post-transcriptionally modified ...
Nancy L Craig +5 more
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This chapter explores RNA processing events, which are points for regulation and quality control, and are sources of diversity. Many RNA processing reactions are directed by RNA components. Transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs) are processed out of longer precursor transcripts, and the nucleotides are post-transcriptionally modified ...
Nancy L Craig +5 more
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Annual Review of Biochemistry, 1976
CONTENTS PERSPECTIVES AND SUMMARY tRNA . Prokaryotes , . Eukaryotes . rRNA . Prokaryotes , , , ... .
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CONTENTS PERSPECTIVES AND SUMMARY tRNA . Prokaryotes , . Eukaryotes . rRNA . Prokaryotes , , , ... .
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Current Opinion in Cell Biology, 1991
Continued progress has been made during the past year in understanding the basic biochemical mechanisms involved in nuclear RNA processing. Of particular importance have been the advances made in purifying and characterizing protein factors involved in splicing and polyadenylation of pre-mRNAs.
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Continued progress has been made during the past year in understanding the basic biochemical mechanisms involved in nuclear RNA processing. Of particular importance have been the advances made in purifying and characterizing protein factors involved in splicing and polyadenylation of pre-mRNAs.
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Small Nuclear RNAs and RNA Processing
1983I. Summary Ribosomal RNA, transfer RNA, and messenger RNAs, which comprise about 99% of the cellular RNA, are part of the protein-synthesizing machinery. Many studies in the last 15 years have established the presence of another class of RNA, “small nuclear RNAs” (snRNAs) that account for 0.1-1% of the total cellular RNA.
R, Reddy, H, Busch
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An RNA Processing Activity That Debranches RNA Lariats
Science, 1985The excised introns of pre-messenger RNA's (pre-mRNA's) and intron-containing splicing intermediates are in a lariat configuration in which the 5′ end of the intron is covalently joined by a 2′,5′-phosphodiester bond to a specific adenosine residue near the 3′ end of the intron. A 2′,5′-phosphodiesterase activity in HeLa cell extracts has been detected
B, Ruskin, M R, Green
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RNA processing in prokaryotic cells
BioEssays, 1993AbstractRNA processing in Escherichia coli and some of its phages is reviewed here, with primary emphasis on rRNA and tRNA processing. Three enzymes, RNase III, RNase E and RNase P are responsible for most of the primary endonucleolytic RNA processing events. The first two are proteins, while RNase P is a ribozyme.
D, Apirion, A, Miczak
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Telomerase RNA biosynthesis and processing
Biochemistry (Moscow), 2012Telomerase synthesizes repetitive G-rich sequences (telomeric repeats) at the ends of eukaryotic chromosomes. This mechanism maintains the integrity of the genome, as telomere shortening leads to degradation and fusion of chromosomes. The core components of telomerase are the telomerase catalytic subunit and telomerase RNA, which possesses a small ...
E M, Smekalova +5 more
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