Results 181 to 190 of about 1,879,245 (305)

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Improved downstream functional analysis of single-cell RNA-sequence data using DGAN. [PDF]

Sci Rep, 2023
Pandey D, Onkara PP.
europepmc   +1 more source

An Adenylic Acid-Rich Sequence in Messenger RNA of HeLa Cells and Its Possible Relationship to Reiterated Sites in DNA

, 1971
James Darnell, Randolph Wall, Robert Tushinski   +2 more
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Insertions and deletions in the RNA sequence-structure map. [PDF]

J R Soc Interface, 2021
Martin NS, Ahnert SE.
europepmc   +1 more source

Complementary sequences 1700 nucleotides apart form a ribonuclease III cleavage site in Escherichia coli ribosomal precursor RNA.

, 1978
R A Young, Joan A. Steitz
openalex   +1 more source

Nucleotide sequence of the 3′-noncoding region of alfalfa mosaic virus RNA 4 and its homology with the genomic RNAs [PDF]

, 1979
Ellen C. Koper-Zwarthoff, Frans Th. Brederod, Pauline Walstra, John F. Bol   +3 more
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Learning to predict RNA sequence expressions from whole slide images with applications for search and classification. [PDF]

Commun Biol, 2023
Alsaafin A, Safarpoor A, Sikaroudi M, Hipp JD, Tizhoosh HR.   +4 more
europepmc   +1 more source

The Nucleotide Sequence of Methionine Transfer RNA_M [PDF]

, 1970
Suzanne Cory, Kjeld A. Marcker
openalex   +1 more source