Results 151 to 160 of about 1,674,122 (352)

RNA sequence analysis reveals ITGAL/CD11A as a stromal regulator of murine low-grade glioma growth. [PDF]

Neuro Oncol, 2022
De Andrade Costa A, Chatterjee J, Cobb O, Sanapala S, Scheaffer S, Guo X, Dahiya S, Gutmann DH.   +7 more
europepmc   +1 more source

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs [PDF]

, 1987
Marilyn Kozak
openalex   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Workflow Optimization for Identification of Female Germline or Oogonial Stem Cells in Human Ovarian Cortex Using Single-Cell RNA Sequence Analysis. [PDF]

Stem Cells, 2022
Alberico H, Fleischmann Z, Bobbitt T, Takai Y, Ishihara O, Seki H, Anderson RA, Telfer EE, Woods DC, Tilly JL.   +9 more
europepmc   +1 more source

Isolation of Unknown Genes from Human Bone Marrow by Differental Screening and Single-Pass cDNA Sequences Determination [PDF]

, 1994
A cDNA sequencing project was initiated to characterize gene expression in human bone marrow and develop strategies to isolate novel genes. Forty-eight random cDNAs from total human bone marrow were subjected to single-pass DNA sequence analysis to ...
Hood, Leroy, Hughes, Tim P., Kato, Roberta M., Orr, Sally R., Quan, Shirley G., Sawyers, Charles L., Williams, Suzanne P., Witte, Owen N.   +7 more
core  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Nucleotide sequence analysis of precursor 5S RNA from Bacillus licheniformis [PDF]

, 1980
Willem J. Stiekema, Rita de Leede-Twente, Hendrik A. Raué, Rudi J. Planta   +3 more
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Optimal alignment algorithm for context-sensitive hidden Markov models [PDF]

, 2005
The hidden Markov model is well-known for its efficiency in modeling short-term dependencies between adjacent samples. However, it cannot be used for modeling longer-range interactions between symbols that are distant from each other.
Vaidyanathan, P. P., Yoon, Byung-Jun
core   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source