Results 171 to 180 of about 293,102 (292)

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

Advanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu, Wuhui He, Yun Xiao, Qiong Wu, Qing Zhang, Tiesong Zhang, Lei Xu, Xinyi Pang   +7 more
wiley   +1 more source

A pectin acetyl-transferase facilitates secondary plasmodesmata formation and RNA silencing movement between plant cells. [PDF]

Plant J
Jay F, Brioudes F, Novaković L, Imboden A, Benitez-Alfonso Y, Voinnet O.   +5 more
europepmc   +1 more source

RNA-guided RNA silencing by an Asgard archaeal Argonaute

, 2023
Bastiaanssen C, Ugarte PB, Kim K, Feng Y, Finocchio G, Anzelon TA, Köstlbacher S, Tamarit D, Ettema TJG, Jinek M, MacRae IJ, Joo C, Swarts DC, Wu F.   +13 more
europepmc   +1 more source

Genome-wide analysis of key gene families in RNA silencing and their responses to biotic and drought stresses in adzuki bean. [PDF]

BMC Genomics, 2023
Li Y, Ma E, Yang K, Zhao B, Li Y, Wan P.
europepmc   +1 more source

Faculty Opinions recommendation of A viral protein suppresses RNA silencing and binds silencing-generated, 21- to 25-nucleotide double-stranded RNAs.

, 2002
Marjori Matzke
openalex   +2 more sources

Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: Enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition [PDF]

, 2004
Dong Wang, Meihua Luo, Mark R. Kelley
openalex   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Proteolytic control of the RNA silencing machinery. [PDF]

Plant Cell
Genschik P, Schiaffini M, Lechner E.
europepmc   +1 more source

Turnip crinkle virus-encoded suppressor of RNA silencing interacts with Arabidopsis SGS3 to enhance virus infection. [PDF]

Mol Plant Pathol, 2023
Liu L, Wang H, Fu Y, Tang W, Zhao P, Ren Y, Liu Z, Wu K, Zhang X.   +8 more
europepmc   +1 more source

Faculty Opinions recommendation of Spreading of RNA targeting and DNA methylation in RNA silencing requires transcription of the target gene and a putative RNA-dependent RNA polymerase.

, 2002
James C. Carrington
openalex   +1 more source