Results 191 to 200 of about 365,878 (302)

Response to "Antiviral RNA silencing in mammals: the importance of selecting the appropriate experimental model". [PDF]

Nucleic Acids Res
Svoboda P, Malik R.
europepmc   +1 more source

Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction

Advanced Science, EarlyView.
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao, Shenghui Huo, Yue Xing, Shuxin Zhang, Guilin Li, Yihui Liu, Chongyang Jin, Fuguang Li, Xiaoyang Ge   +8 more
wiley   +1 more source

Plant Extracellular Vesicles with Complex Molecular Cargo: A Cross-Kingdom Conduit for MicroRNA-Directed RNA Silencing. [PDF]

Genes (Basel)
Shalvina A, Paul NA, Cummins SF, Eamens AL.   +3 more
europepmc   +1 more source

ER-associated RNA silencing promotes ER quality control. [PDF]

Nat Cell Biol, 2022
Efstathiou S, Ottens F, Schütter LS, Ravanelli S, Charmpilas N, Gutschmidt A, Le Pen J, Gehring NH, Miska EA, Bouças J, Hoppe T.   +10 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Potato Virus Y NIb Multifunctional Protein Suppresses Antiviral Defense by Interacting with Several Protein Components of the RNA Silencing Pathway. [PDF]

Int J Mol Sci
Niraula PM, Howell S, Stratton CA, Moore MT, Dopler MB, Abeer MI, Gitcho MA, Fondong VN.   +7 more
europepmc   +1 more source

RNA silencing proteins and small RNAs in oomycete plant pathogens and biocontrol agents. [PDF]

Front Microbiol, 2023
Piombo E, Kelbessa BG, Sundararajan P, Whisson SC, Vetukuri RR, Dubey M.   +5 more
europepmc   +1 more source

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

Advanced Science, EarlyView.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu, Jianwei Wang, Zhiheng Li, Qi Ji, Hui Zhang, Qinyi Zhang, Senlin Zhang, Juanjuan Yu, Yanfang Tao, Yijun Wu, Chunxia Shi, Zong Zai, Zimu Zhang, Yizhen Li, Zhenjiang Bai, Shaoyan Hu, Jian Pan, Yang Yang, Shuiyan Wu   +18 more
wiley   +1 more source

Antiviral RNA silencing in mammals: the importance of selecting the appropriate experimental model. [PDF]

Nucleic Acids Res
Liu X, Li Y.
europepmc   +1 more source

Role of RNA silencing in plant-viroid interactions and in viroid pathogenesis. [PDF]

Virus Res, 2023
Di Serio F, Owens RA, Navarro B, Serra P, Martínez de Alba ÁE, Delgado S, Carbonell A, Gago-Zachert S.   +7 more
europepmc   +1 more source