U1 small nuclear RNAs with altered specificity can be stably expressed in mammalian cells and promote permanent changes in pre-mRNA splicing. [PDF]
, 1993 Justus B. Cohen +2 more
openalex +2 more sources
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Advanced Science, EarlyView.Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu +13 more
wiley +1 more source
Therapeutic potential of alternative splicing in cardiovascular diseases
EBioMedicineSummary: RNA splicing is an important RNA processing step required by multiexon protein-coding mRNAs and some noncoding RNAs. Precise RNA splicing is required for maintaining gene and cell function; however, mis-spliced RNA transcripts can lead to loss ...
Jun Cao, Ziyu Wei, Yu Nie, Hou-Zao Chen
doaj
Unlocking the therapeutic potential of RNA splicing in lung fibrosis: Insights from the SRSF7-PKM axis. [PDF]
Acta Pharm Sin BDing BS.
europepmc +1 more source
Coronavirus leader‐RNA‐primed transcription: An alternative mechanism to RNA splicing
, 1986 Michael M. C. Lai
openalex +1 more source
Multiple Rh messenger RNA isoforms are produced by alternative splicing [PDF]
, 1992 Caroline Le Van Kim +6 more
openalex +1 more source
Engineered Foxp1high Exosomes Ameliorates Systemic Lupus Erythematosus
Advanced Science, EarlyView.This study presents a dual‐engineering strategy combining mesenchymal stem cell aggregation and Foxp1 overexpression to generate Foxp1high aggregation exosomes with enhanced immunomodulatory properties. These engineered exosomes exhibit immune organ targeting and superior efficacy in systemic lupus erythematosus treatment by promoting Treg ...
Luhan Niu +9 more
wiley +1 more source
The mitochondrial tyrosyl-tRNA synthetase of Podospora anserina is a bifunctional enzyme active in protein synthesis and RNA splicing. [PDF]
, 1992 U Kämper +3 more
openalex +1 more source
Advanced Science, EarlyView.This study investigates the role of group 2 innate lymphoid cells (ILC2) in the choroid plexus (ChP) following traumatic brain injury (TBI). ILC2 accumulation alleviates immune infiltration, preserves hippocampal integrity, and improves sensory‐motor and memory functions.
Shiqi Gao +10 more
wiley +1 more source
Intrinsic <i>Alu</i> affects for RNA splicing in a minigene model. [PDF]
Biochem Biophys RepNakama M, Imanaka B, Kimoto Y.
europepmc +1 more source