Results 151 to 160 of about 1,384,640 (333)

Graphmap2 - splice-aware RNA-seq mapper for long reads [PDF]

, 2019
Josip Marić, Ivan Sović, Krešimir Križanović, Niranjan Nagarajan, Mile Šikić   +4 more
openalex   +1 more source

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

Advanced Science, EarlyView.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu, Dittman Lai‐Shun Chung, Larry Ka‐Yue Chow, Shuo Han, Wenkai Yi, Conor J. Cremin, Yingyin Liao, Pui Wang, Bobo Wing‐Yee Mok, Mingfang Ji, Jian Yan, Wei Dai, Honglin Chen   +12 more
wiley   +1 more source

Interrogations of single-cell RNA splicing landscapes with SCASL define new cell identities with physiological relevance

Nature Communications
RNA splicing shapes the gene regulatory programs that underlie various physiological and disease processes. Here, we present the SCASL (single-cell clustering based on alternative splicing landscapes) method for interrogating the heterogeneity of RNA ...
Xianke Xiang, Yao He, Zemin Zhang, Xuerui Yang   +3 more
doaj   +1 more source

Single‐Cell Transcriptome Atlas Reveals the Underlying Mechanism of Kynurenic Acid in the Regulation of Tumor Immune Microenvironment in Glioblastoma

Advanced Science, EarlyView.
KYNA regulates the tumor immune microenvironment in glioblastoma. KYNA reprograms the balance between T cell exhaustion and activation to suppress glioblastoma progression through inhibiting exhaustion‐associated markers (such as PD‐1, LAG3, and TOX) and enhancing immune activation and cytotoxicity markers including granzymes GZMA and GZMB.
Di Chen, Liming Sun, Jiajun Chen, Zi Ye, Xuqiang Zhu, Hongjiang Li, Lixin Wu, Guohua Zhao, Qinghao Zhang, Guangyi Jiang, Yuchen Ji, Yake Xue, Hongwei Li, Ruokun Chen, Hongwei Zheng, Rong Zeng, Dongming Yan, Yong Zhang, Xueyuan Li, Jing Yan   +19 more
wiley   +1 more source

Conjugation of PEG and gold nanoparticles to increase the accessibility and valency of tethered RNA splicing enhancers

, 2012
Andrew J. Perrett, Rachel L. Dickinson, Željka Krpetić, Mathias Brust, Helen Lewis, Ian C. Eperon, Glenn A. Burley   +6 more
openalex   +2 more sources

An alternative Pit-1 RNA splicing product reveals modular binding and nonmodular transcriptional activities of the POU-specific domain. [PDF]

, 1993
J W Voss, L Wilson, Simon J. Rhodes, Michael G. Rosenfeld   +3 more
openalex   +1 more source

The Global Protein-Rna Interaction Map of Epithelial Splicing Regulatory Protein 1 Defines a Post-Transcriptional Program that is Essential for Epithelial Cell Function

, 2021
Natoya Peart, Jae Yeon Hwang, Mathieu Quesnel-Vallières, Matthew J. Sears, Yueqin Yang, Peter Stoilov, Yoseph Barash, Juw Won Park, Russ P. Carstens   +8 more
openalex   +1 more source

RNA splicing is a primary link between genetic variation and disease

Science, 2016
Yang I. Li, Bryce van de Geijn, Anil Raj, David A. Knowles, A. Petti, David Golan, Y. Gilad, J. Pritchard   +7 more
semanticscholar   +1 more source

IPGCA: A Comprehensive Single Cell Atlas of 1 074 127 Porcine Intestinal Cells Revealing Cellular Dynamics, Genetic Regulation, and Cross‐Species Conservation

Advanced Science, EarlyView.
A high resolution integrated cell atlas of the pig intestine provides insights into the genetic mechanisms of complex traits (Created in BioRender. Yu, P. (2025) https://BioRender.com/o14c563) Abstract The porcine intestinal tract is vital for nutrient absorption, immune regulation, and various physiological processes.
Pengfei Yu, Qinqin Xie, Xiaodian Cai, Zhanming Zhong, Ran Wei, He Han, Shuang Liu, Zhenyang Zhang, Lingyao Xu, Zitao Chen, Zhe Zhang, Qishan Wang, Yuchun Pan, Zhen Wang, Zhe Zhang   +14 more
wiley   +1 more source

Supplementary table from Integrative RNA-omics Discovers <i>GNAS</i> Alternative Splicing as a Phenotypic Driver of Splicing Factor–Mutant Neoplasms

, 2023
Emily C. Wheeler, Shailee Vora, Daniel Mayer, Andriana G. Kotini, Małgorzata Olszewska, Samuel S. Park, Ernesto Guccione, Julie Teruya‐Feldstein, Lewis B. Silverman, Roger K. Sunahara, G Yeo, Eirini P. Papapetrou   +11 more
openalex   +1 more source