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Integrated Immune Landscape Analysis of RNA Splicing Factor-Mutant AML and Higher risk MDS Treated with Azacitidine ± Durvalumab. [PDF]

open access: yesTher Adv Hematol
Bewersdorf JP   +14 more
europepmc   +1 more source
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RNA Splicing and Cancer

Trends in Cancer, 2020
RNA splicing is an essential process that governs many aspects of cellular proliferation, survival, and differentiation. Considering the importance of RNA splicing in gene regulation, alterations in this pathway have been implicated in many human cancers.
Eric, Wang, Iannis, Aifantis
openaire   +2 more sources

RNA Trans-Splicing

1992
RNA trans-splicing joins two or more RNA molecules into one RNA molecule. This process is a variation of the more familiar and common intron removal during nuclear pre-mRNA splicing. Both splicing reactions are a series of cleavage and ligation reactions resulting in the precise excision of introns and in the joining of exons to generate mature RNA. In
X Y, Huang, D, Hirsh
openaire   +2 more sources

DNA-catalysed alternative RNA splicing

Chemical Communications, 2022
DNA can catalyse alternative RNA splicing reactionsin vitro, and modulate RNA structure and function.
Dongying Wei   +6 more
openaire   +2 more sources

Circular RNA Splicing

2018
Circular RNAs (circRNAs) are covalently closed single-stranded RNA molecules derived from exons by alternative mRNA splicing. Circularization of single-stranded RNA molecules was already described in 1976 for viroids in plants. Since then several additional types of circular RNAs in many species have been described such as the circular single-stranded ...
Nicole, Eger   +4 more
openaire   +2 more sources

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