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Visualizing RNA splicing in vivo
Molecular BioSystems, 2007Ribozymes are RNA molecules capable of associating with other RNA molecules through base-pairing and catalyzing various reactions involving phosphate group transfer. Of particular interest to us is the well known ribozyme from Tetrahymena thermophila capable of catalyzing RNA splicing in eukaryotic systems, chiefly because of its potential use as a ...
Gayatri Gowrishankar, Jianghong Rao
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RNA Splicing: Activity in the spliceosome
Current Biology, 1994In the active spliceosome, U2, U5 and U6 small nuclear RNAs form a network of interactions with the RNA substrate. U6 snRNA is closely implicated in the catalysis of splicing.
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RNA Trans-Splicing for Genodermatoses
2012Spliceosome-mediated RNA trans-splicing (SMaRT) is a tool that facilitates the recombination of two distinct pre-mRNA molecules. Its application for gene therapeutic purposes has been hindered by laborious procedures to identify gene-specific molecules.
Ulrich Koller +3 more
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1989
Trans-splicing is a recently discovered phenomenon defined as the splicing together of two discrete RNA molecules to give a single hybrid RNA product. There are two distinct types of physiological trans-splicing. The first is found in organelles of eukaryotes.
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Trans-splicing is a recently discovered phenomenon defined as the splicing together of two discrete RNA molecules to give a single hybrid RNA product. There are two distinct types of physiological trans-splicing. The first is found in organelles of eukaryotes.
openaire +2 more sources