Results 171 to 180 of about 511,041 (280)

Unexpected Role of Sterol Synthesis in RNA Stability and Translation in Leishmania. [PDF]

Biomedicines, 2021
Karamysheva ZN, Moitra S, Perez A, Mukherjee S, Tikhonova EB, Karamyshev AL, Zhang K.   +6 more
europepmc   +1 more source

Nonsynonymous Mutations in Linker-2 of the Pdr5 Multidrug Transporter Identify a New RNA Stability Element [PDF]

, 2019
Hadiar Rahman, Andrew Rudrow, Joshua Carneglia, Sister Stephen Patrick Joly, Dante J. Nicotera, Michael J. Naldrett, John S. Choy, Suresh V. Ambudkar, John Golin   +8 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

NSUN2-mediated HCV RNA m5C Methylation Facilitates Viral RNA Stability and Replication. [PDF]

Genomics Proteomics Bioinformatics
Li ZL, Xie Y, Wang Y, Wang J, Zhou X, Zhang XL.   +5 more
europepmc   +1 more source

SARS-CoV-2 RNA stability in dry swabs for longer storage and transport at different temperatures. [PDF]

Transbound Emerg Dis, 2022
Alfaro-Núñez A, Crone S, Mortensen S, Rosenstierne MW, Fomsgaard A, Marving E, Nielsen SH, Jørgensen MGP, Polacek C, Cohen AS, Nielsen C.   +10 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Transcriptome-scale analysis uncovers conserved residues in the hydrophobic core of the bacterial RNA chaperone Hfq required for small regulatory RNA stability. [PDF]

Nucleic Acids Res
McQuail J, Krepl M, Katsuya-Gaviria K, Tabib-Salazar A, Burchell L, Bischler T, Gräfenhan T, Brear P, Šponer J, Luisi BF, Wigneshweraraj S.   +10 more
europepmc   +2 more sources

Structural analyses of an RNA stability element interacting with poly(A). [PDF]

Proc Natl Acad Sci U S A, 2021
Torabi SF, Chen YL, Zhang K, Wang J, DeGregorio SJ, Vaidya AT, Su Z, Pabit SA, Chiu W, Pollack L, Steitz JA.   +10 more
europepmc   +1 more source

Interactome Analysis of the Human Respiratory Syncytial Virus RNA Polymerase Complex Identifies Protein Chaperones as Important Cofactors That Promote L-Protein Stability and RNA Synthesis [PDF]

, 2014
Diane C. Munday, Weining Wu, Darren Smith, Jenna Fix, Sarah L. Noton, Marie Galloux, Olivier Touzelet, Stuart D. Armstrong, Jenna M. Dawson, Waleed Aljabr, Andrew J. Easton, Marie‐Anne Rameix‐Welti, Andressa Peres de Oliveira, Fernando Moreira Simabuco, Armando Morais Ventura, David J. Hughes, John N. Barr, Rachel Fearns, Paul Digard, Jean‐François Eléouët, Julian A. Hiscox   +20 more
openalex   +1 more source

4′-C-Aminoethoxy modification enhanced nuclease resistance of RNAs and improved thermal stability of RNA duplexes

, 2021
Ryo Tsukimura, Ryohei Kajino, Yujun Zhou, Akash Chandela, Yoshihito Ueno   +4 more
openalex   +1 more source