Results 181 to 190 of about 511,041 (280)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Single Nucleotide Polymorphisms of Porcine lncMGPF Regulate Meat Production Traits by Affecting RNA Stability. [PDF]

Front Cell Dev Biol, 2021
Lv W, Zhao S, Hou Y, Tong Q, Peng Y, Li J, Xu Z, Zuo B.   +7 more
europepmc   +1 more source

Stability of HIV RNA in plasma specimens stored at different temperatures [PDF]

, 2008
Bahia Amellal, Robert L. Murphy, Almoustapha Issiaka Maïga, Gilles Brücker, Christine Katlama, Vincent Cálvez, Anne‐Geneviève Marcelin   +6 more
openalex   +1 more source

Effect of Water Models on The Stability of RNA: Role of Counter-Ions

, 2023
Omkar Singh, Pushyaraga P. Venugopal, Debashree Chakraborty   +2 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Epitranscriptomic addition of m⁶A regulates HIV-1 RNA stability and alternative splicing. [PDF]

Genes Dev, 2021
Tsai K, Bogerd HP, Kennedy EM, Emery A, Swanstrom R, Cullen BR.   +5 more
europepmc   +1 more source

Determining The Stability Of Hiv-1 Rna In Plasma Samples Stored At Various Temperatures In Primary Tubes Of Centrifuged Whole Blood

N Lesesa, Pakiso Moses Makhoahle, K Mapolosi   +2 more
openalex   +2 more sources

Global Maps of ProQ Binding In Vivo Reveal Target Recognition via RNA Structure and Stability Control at mRNA 3′ Ends [PDF]

, 2018
Erik Holmqvist, Lei Li, Thorsten Bischler, Lars Barquist, Jörg Vogel   +4 more
openalex   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

The N6-methyladenosine landscape of ovarian development and aging highlights the regulation by RNA stability and chromatin state. [PDF]

Aging Cell
Hu X, Lu J, Ding C, Li J, Zou Q, Xia W, Qian C, Li H, Huang B.   +8 more
europepmc   +1 more source