Results 241 to 250 of about 4,719,315 (357)

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

An Evolutionarily Conserved AU-Rich Element in the 3' Untranslated Region of a Transcript Misannotated as a Long Noncoding RNA Regulates RNA Stability. [PDF]

Mol Cell Biol, 2022
Dangelmaier EA, Li XL, Hartford CCR, King JC, Zibitt MS, Chari R, Grammatikakis I, Lal A.   +7 more
europepmc   +1 more source

The N6-methyladenosine landscape of ovarian development and aging highlights the regulation by RNA stability and chromatin state. [PDF]

Aging Cell
Hu X, Lu J, Ding C, Li J, Zou Q, Xia W, Qian C, Li H, Huang B.   +8 more
europepmc   +1 more source

Tailoring the evolution of BL21(DE3) uncovers a key role for RNA stability in gene expression toxicity. [PDF]

Commun Biol, 2021
Heyde SAH, Nørholm MHH.
europepmc   +1 more source

Phenotypic and Genetic Stability of Petunias Expressing Sense and Antisense RNAs of Endogenous Genes [PDF]

, 1995
William R. Woodson
openalex   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Osmotic pressure‐induced calcium response states

FEBS Open Bio, EarlyView.
Acute hypotonic stress triggers distinct calcium response patterns in HEK293T cells. These signals originate from the endoplasmic reticulum via RyR2 and propagate to neighboring cells through gap junctions. This result highlights a novel calcium‐dependent mechanism underlying the intracellular and intercellular response to osmotic pressure.
Zidan Gao, Keiji Naruse, Masatoshi Morimatsu   +2 more
wiley   +1 more source

Modulation of RNA stability regulates gene expression in two opposite ways: through buffering of RNA levels upon global perturbations and by supporting adapted differential expression. [PDF]

Nucleic Acids Res, 2022
Faucillion ML, Johansson AM, Larsson J.
europepmc   +1 more source

Effects of specimen collection, processing, and storage conditions on stability of human immunodeficiency virus type 1 RNA levels in plasma

, 1997
Christine C. Ginocchio, X P Wang, Mark H. Kaplan, Guy B. Mulligan, Donald J. Witt, Joseph Romano, Michael Cronin, Richard G. Carroll   +7 more
openalex   +1 more source

Corrigendum: Single nucleotide polymorphisms of porcine lncMGPF regulate meat production traits by affecting RNA stability. [PDF]

Front Cell Dev Biol
Lv W, Zhao S, Hou Y, Tong Q, Peng Y, Li J, Xu Z, Zuo B.   +7 more
europepmc   +1 more source