Results 221 to 230 of about 1,943,814 (363)

Inhibition of RNA polymerase and formyltetrahydrofolate synthetase activity by 6‐chloro‐8‐aza‐9‐cyclopentylpurine. Structure‐activity relationships [PDF]

, 1970
Raymond W. Ruddon, Cynthia H. Rainey, Morris S. Zedeck   +2 more
openalex   +1 more source

Compound Heterozygous MRPS14 Variants Associated With Leigh Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT MRPS14 (uS14m) is a nuclear‐encoded ribosomal protein important for mitochondria‐specific translation. To date, only a single individual with a recessive MRPS14‐related disorder (also known as COXPD38) has been reported. We report an additional subject possessing novel compound heterozygous MRPS14 variants (p.Asp37Asn, p.Asn60Asp). The subject
Maria Gabriela Otero, Christina Freeman, Ruchi Shah, Renkui Bai, Hong Cui, Marian Castro, Zachary Myers, Eric Choy, Derek Chan, Molly Easter, Sophia Y. Zhao, Madeline Babros, Ruchi Garg, Matthew Deardorff, Franklin Moser, Tyler Mark Pierson   +15 more
wiley   +1 more source

IPANEMAP Suite: a pipeline for probing-informed RNA structure modeling. [PDF]

NAR Genom Bioinform
Hardouin P, Pan N, Lyonnet du Moutier FX, Chamond N, Ponty Y, Will S, Sargueil B.   +6 more
europepmc   +1 more source

Observation of coordinated RNA folding events by systematic cotranscriptional RNA structure probing. [PDF]

Nat Commun, 2023
Szyjka CE, Strobel EJ.
europepmc   +1 more source

DNA-dependent RNA polymerases from Artemia salina. Subunit structure of polymerase II [PDF]

, 1976
J.C. Bagshaw
openalex   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Bioorthogonal Cyclopropenones for Investigating RNA Structure. [PDF]

ACS Chem Biol
Chen S, Sibley CD, Latifi B, Balaratnam S, Dorn RS, Lupták A, Schneekloth JS, Prescher JA.   +7 more
europepmc   +1 more source

A rapid and facile procedure for the preparation of RNA polymerase I from Acanthamoeba castellanii. Purification and subunit structure

, 1978
S R Spindler, Gregg Duester, James M. D'Alessio, Marvin R. Paule   +3 more
openalex   +1 more source

Secondary Structure of the 5′ End of Bacteriophage MS2 RNA [PDF]

, 1979
D. Iserentant, Walter Fiers
openalex   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source