Results 231 to 240 of about 15,140,513 (376)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

APE1 condensation in nucleoli of non-cancer cells depends on rRNA transcription and forming G-quadruplex RNA structures

Giuseppe Dall’Agnese, Nancy M. Hannett, Kalon J. Overholt, Jesse M. Platt, Jonathan E. Henninger, Asier Marcos-Vidal, Zulhabri Othman, Gilmar F. Salgado, Giulia Antoniali, Gianluca Tell   +9 more
openalex   +1 more source

Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNA

, 2009
Andrej Kolarovič, Emma Schweizer, Emily M. Greene, Mark Gironda, Pradeep S. Pallan, Martin Egli, Eriks Rozners   +6 more
openalex   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

A CRISPR mis-insertion in the Zic3 5′UTR inhibits in vivo translation and is predicted to result in formation of an mRNA stem-loop hairpin

Biology Open
Helen M. Bellchambers, Maria B. Padua, Stephanie M. Ware   +2 more
doaj   +1 more source

Thermodynamics and kinetics of RNA tertiary structure formation in the junctionless hairpin ribozyme

, 2017
Neil A. White, Charles G. Hoogstraten
openalex   +2 more sources

In-cell RNA structure probing with SHAPE-MaP

Nature Protocols, 2018
M. J. Smola, K. Weeks
semanticscholar   +1 more source

Influence of contact map topology on RNA structure prediction. [PDF]

Nucleic Acids Res
Faber C, Upadhyay U, Taubert O, Schug A.
europepmc   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo

Nature Methods, 2016
Meghan M. Zubradt, Paromita Gupta, S. Persad, A. Lambowitz, J. Weissman, Silvi Rouskin   +5 more
semanticscholar   +1 more source