Results 181 to 190 of about 813,434 (316)

RNA virus polymerase-helicase coupling enables rapid elongation through duplex RNA. [PDF]

Cell Rep
America PPB, Bera SC, Das A, Anderson TK, Marecki JC, Papini FS, Arnold JJ, Kirchdoerfer RN, Cameron CE, Raney KD, Depken M, Dulin D.   +11 more
europepmc   +1 more source

Sequence analysis of the small (s) RNA segment of viruses in the genus Orthobunyavirus

, 2007
Viruses in the genus Orthobunyavirus (family Bunyaviridae) are classified serologically into 18 serogroups. The viruses have a tripartite genome of negative sense RNA composed of large (L), medium (M) and small (S) segments.
Mohamed, Maizan
core  

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Editorial: High-impact respiratory RNA virus diseases, volume II. [PDF]

Front Vet Sci
Petrone-Garcia VM, Juárez-Estrada MA, Fuente B, Castellanos-Huerta I.   +3 more
europepmc   +1 more source

Defective interfering particles of parainfluenza virus subtype 5 and interferon induction

, 2015
The innate immune response is the first line of defence against virus infection. Cells contain a diverse array of pathogen recognition receptors (PRRs) that are able to recognise multiple pathogen associated molecular patterns (PAMPS) that present ...
Short, John A. L.
core  

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

The Regulation of Oxidative Stress Is a Conserved Response to RNA Virus Infection in Fish. [PDF]

Antioxidants (Basel)
Romero A, Pereiro P, Figueras A, Novoa B.   +3 more
europepmc   +1 more source

Virus-encoded RNA helicases [PDF]

Journal of Virology, 1997
G, Kadaré, A L, Haenni
openaire   +2 more sources

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

The inhibition mechanism of <i>Wolbachia</i> on mosquito-borne RNA virus replication as seen through lipid metabolism regulation. [PDF]

Front Microbiol
Wang Z, Cui X, Zhang Q, Zou L, Wang J.
europepmc   +1 more source