Results 211 to 220 of about 1,185,737 (360)

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche   +8 more
wiley   +1 more source

Apoptotic metabolites synthesize and inherit unique de novo L2a/L2b RNAs to prevent virus infection

open access: gold
Peiyi Li   +14 more
openalex   +1 more source

Virus and host interactions critical for filoviral RNA synthesis as therapeutic targets

open access: green, 2018
Christopher F. Basler   +3 more
openalex   +2 more sources

Gold nanoparticle-based delivery of Cas13d for targeted RNA virus defense. [PDF]

open access: yesMol Ther Nucleic Acids
Alves da Silva NJ   +3 more
europepmc   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney   +3 more
wiley   +1 more source

microRNA-122 stimulates translation of hepatitis C virus RNA [PDF]

open access: bronze, 2008
Jura Inga Henke   +7 more
openalex   +1 more source

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