Results 231 to 240 of about 1,185,737 (360)

Phosphorylation of Hepatitis C Virus RNA Polymerases Ser29 and Ser42 by Protein Kinase C-Related Kinase 2 Regulates Viral RNA Replication [PDF]

, 2014
Song-Hee Han, Seong-Jun Kim, Eun‐Jung Kim, Tae-Eun Kim, Jae-Su Moon, Geon‐Woo Kim, Seung‐Hoon Lee, Kun Cho, Jong Shin Yoo, Woo Sung Son, Jin‐Kyu Rhee, Seung Hyun Han, Jong‐Won Oh   +12 more
openalex   +1 more source

hnRNPA2B1 recognizes RNA virus SFTSV infection through mitochondrial DNA. [PDF]

mBio
Huang X-b, Zhang Y, Fan J-w, Yu X-y, Fang Y-l, Ren J-x, Liu B-y.   +6 more
europepmc   +1 more source

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, EarlyView.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

Negative-sense RNA virus nucleocapsid as a versatile platform for gene delivery, vaccine development, and antiviral screening. [PDF]

Sci Rep
Rehman S, Chavan PM, Chaturvedi A, Nayak D.   +3 more
europepmc   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

s8ORF2 protein of infectious salmon anaemia virus is a RNA-silencing suppressor and interacts with Salmon salar Mov10 (SsMov10) of the host RNAi machinery [PDF]

, 2017
Vandana Thukral, Bhavna Varshney, Rimatulhana Ramly, Sanket S. Ponia, Sumona Karjee Mishra, Christel M. Olsen, Akhil C. Banerjea, Sunil Kumar Mukherjee, Rana Zaidi, Espen Rimstad, Sunil K. Lal   +10 more
openalex   +1 more source

Determination of Chikungunya Virus RNA by Reverse Transcription Loop-Mediated Isothermal Amplification (RT-LAMP) Assay

, 2022
Barnali Sen, Sabrina Afrin, Sharmin Zahan, Saif Ullah Munshi, Sifat Uz Zaman   +4 more
openalex   +2 more sources

A heritable RNA virus facilitates egg hatching of a parasitoid wasp. [PDF]

Ann Entomol Soc Am
Izraeli Y, Wodowski G, Mozes-Daube N, Varaldi J, Zchori-Fein E, Chiel E.   +5 more
europepmc   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

From disorder to icosahedral symmetry: How conformation-switching subunits enable RNA virus assembly. [PDF]

Sci Adv
Li S, Tresset G, Zandi R.
europepmc   +1 more source