Exploring the significant genetic diversity of Iranian isolates of Leishmania RNA virus 2 using whole genome sequence analysis. [PDF]
Saberi R+4 more
europepmc +1 more source
RFWD3 Reprograms Nucleotide Metabolism Through PHGDH to Induce Chemoresistance In Osteosarcoma
RFWD3 is identified as a key regulator of cisplatin (DDP) sensitivity in osteosarcoma using a genome‐wide CRISPR screen. RFWD3 promotes PHGDH ubiquitination, enhancing NAD+‐mediated nucleotide biosynthesis. Knocking out RFWD3 sensitized osteosarcoma cells to DDP.
Wenchao Zhang+6 more
wiley +1 more source
Positive-strand RNA virus replication organelles at a glance.
Stancheva VG, Sanyal S.
europepmc +1 more source
VirTAXA: enhancing RNA virus taxonomic classification with remote homology search and tree-based validation. [PDF]
Zhu Y, Chen G, Sun Y.
europepmc +1 more source
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao+11 more
wiley +1 more source
Unchecked growth: Pushing the limits on RNA virus genome size in the absence of known proofreading. [PDF]
Glasner DR, Daugherty MD.
europepmc +1 more source
Interferon and Transcription of Early Virus-Specific RNA in Cells Infected with Simian Virus 40
Michael N. Oxman, Myron J. Levin
openalex +1 more source
Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion
Chemotherapy induces DNA damage, activating cyclic guanosine monophosphate (GMP)‐adenosine monophosphate (AMP) synthase (cGAS)/stimulator of interferon genes (STING), which phosphorylates interferon regulatory factor 7 (IRF7) to drive SERTA‐containing domain 1 (SEI1) transcription.
Rui Chen+9 more
wiley +1 more source
Using structure prediction of negative sense RNA virus nucleoproteins to assess evolutionary relationships. [PDF]
Sabsay KR, Te Velthuis AJW.
europepmc +2 more sources