Results 281 to 290 of about 1,185,737 (360)

Ultrasensitive electrochemical genosensor for direct detection of specific RNA sequences derived from avian influenza viruses present in biological samples

, 2019
Kamila Malecka, Edyta Świętoń, Peter Verwilst, Anna Stachyra, Agnieszka Sirko, Wim Dehaen, Jerzy Radecki, Hanna Radecka   +7 more
openalex   +2 more sources

SegFinder: an automated tool for identifying complete RNA virus genome segments through co-occurrence in multiple sequenced samples. [PDF]

Brief Bioinform
Liu X, Kong J, Shan Y, Yang Z, Miao J, Pan Y, Luo T, Shi Z, Wang Y, Gou Q, Yang C, Li H, Li C, Li S, Zhang X, Sun Y, Holmes EC, Guo D, Shi M.   +18 more
europepmc   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

First report of Leishmania RNA virus 2 and its high genetic diversity in cutaneous leishmaniasis cases from Ilam Province, Iran. [PDF]

BMC Med Genomics
Saberi R, Fallahi Lima A, Hajjaran H, Fakhar M.   +3 more
europepmc   +1 more source

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder

Advanced Science, EarlyView.
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai, Mengyao Wu, Anbiao Wu, Zhaofei Jing, Zhenjie Ye, Jiayan Jin, Yaolin Zhang, Min Zhao, Genyu Liu, Xu Wang, Xiqin Yang, Jie Dong, Yunlu Xu, Jiyan Zhang   +13 more
wiley   +1 more source

Evidence for action of ribavirin through the hepatitis C virus RNA polymerase

, 2009
Nathan A. Cannon, Maureen J. Donlin, L. M. Mayes, André Castro Lyra, Adrian M. Di Bisceglie, John E. Tavis   +5 more
openalex   +2 more sources

RNA virus diversity highlights the potential biosecurity threat posed by Antarctic krill. [PDF]

Mar Life Sci Technol
Xu T, Zhao X, Loch T, Zhu J, Wang W, Wang X, Wang C, Fan G, Hao B, Zhang J, Zhao W, Bondad-Reantaso MG, Alday-Sanz V, Zhang Q.   +13 more
europepmc   +1 more source

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

Advanced Science, EarlyView.
ABSTRACT Multiple myeloma (MM) is a hematologic malignancy driven by clonal expansion of malignant plasma cells. Despite the long‐term disease control achieved with immunotherapies in some patients, treatment resistance remains a major cause of disease relapse.
Huiyao Gu, Zhenfeng Dai, Xi Huang, Enfan Zhang, Xinyuan Dai, Haoguang Chen, Wen Cao, Jinna Zhang, Yifan Hou, Haimeng Yan, Yang Yang, Li Yang, Yi Li, Wenlong Lin, Zhen Cai, Jingsong He   +15 more
wiley   +1 more source

Co-opted SUMO machinery promotes condensate formation associated with membranous replication organelles of a positive-strand RNA virus. [PDF]

Proc Natl Acad Sci U S A
Lin W, Nagy PD.
europepmc   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source