Results 311 to 320 of about 1,185,737 (360)

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

The expression profile of inflammatory microRNAs in Leishmania major infected human macrophages; mining the effects of Leishmania RNA virus. [PDF]

BMC Microbiol
Mirabedini Z, Mohebali M, Mirjalali H, Hajjaran H, Goudarzi F, Rahimi HM.   +5 more
europepmc   +1 more source

Development of an RNA virus-based episomal vector with artificial aptazyme for gene silencing. [PDF]

Appl Microbiol Biotechnol
Komorizono R, Yoshizumi S, Tomonaga K.
europepmc   +1 more source

Transcriptional alterations of virulence factors in Leishmania major clinical isolates harboring Leishmania RNA virus 2 (LRV2). [PDF]

BMC Infect Dis
Sabeti S, Koosha M, Kazemirad E, Mirabedini Z, Mohebali M, Saberi R, Fakhar M, Hajjaran H.   +7 more
europepmc   +1 more source

Exploring the impact of a chemical disinfectant and an antiviral drug for RNA virus management in the Mediterranean fruit fly mass-rearing. [PDF]

Insect Sci
Hernández-Pelegrín L, García-Castillo P, Catalá-Oltra M, Dembilio Ó, Ros VID, Herrero S.   +5 more
europepmc   +1 more source

Deciphering mixed infections by plant RNA virus and reconstructing complete genomes simultaneously present within-host. [PDF]

PLoS One
Bangratz M, Comte A, Billard E, Guigma AK, Gandolfi G, Kassankogno AI, Sérémé D, Poulicard N, Tollenaere C.   +8 more
europepmc   +1 more source

Positive-strand RNA virus replication organelles at a glance.

J Cell Sci
Stancheva VG, Sanyal S.
europepmc   +1 more source

Ubiquitination mediates protein localization in RNA virus-infected cells

Shi S, Iesmantavicius V, Sabu AS, Soneson C, Kohler H, Sanchez J, Ghosh S, Cao C, Huang Y, Matthias G, Yamauchi Y, Matthias P, Wang L.   +12 more
europepmc   +1 more source

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RNA virus fitness

Reviews in Medical Virology, 1997
RNA viruses constitute the most abundant group of pathogens of man, animals and plants. They share high mutation rates which are in the range 10(-3) to 10(-5) misincorporations per nucleotide site and round of copying. This is due to the absence or low efficiency of proofreading-repair or postreplicative repair activities associated with replicating ...
, Domingo, , Menéndez-Arias, , Holland
openaire   +2 more sources

RNA-mediated virus resistance

Current Opinion in Biotechnology, 2002
Post-transcriptional gene silencing is an RNA degradation mechanism that can be induced by viruses. Recent evidence indicates that silencing may also be involved in virus synergism, tissue limitation of virus spread, non-host resistance, virus transmission through seeds and in more general mechanisms of defense such as that mediated by salicylic acid ...
Cecilia, Vazquez Rovere, Mariana, del Vas, H Esteban, Hopp   +2 more
openaire   +2 more sources