Optimised Neutralisation Strategies for Validating the Virucidal Efficacy of Micro-Chem Plus™ Against High-Containment Negative-Sense RNA Viruses. [PDF]
Gao X, Peng C, Shan C, Yao Y, Yuan Z.
europepmc +1 more source
An L (polymerase) deficient rabies virus defective interfering particle RNA is replicated and transcribed by heterologous helper virus proteins [PDF]
Conzelmann, Karl-Klaus +2 more
core
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Sequences and Structures of Viral Proteins Linked to the Genomes (VPg) of RNA Viruses. [PDF]
Schein CH.
europepmc +1 more source
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source
Impact of the Zinc Antiviral Protein on the Genomic Composition of RNA Viruses Infecting Vertebrates. [PDF]
Simón D +6 more
europepmc +1 more source
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu +12 more
wiley +1 more source
Metagenomic Investigation of Pathogenic RNA Viruses Causing Diarrhea in Sika Deer Fawns. [PDF]
Wang W +7 more
europepmc +1 more source
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang +14 more
wiley +1 more source
RNA Viruses, Toll-Like Receptors, and Cytokines: The Perfect Storm? [PDF]
Stegeman SK +7 more
europepmc +1 more source

