Results 241 to 250 of about 2,156,375 (387)

Cellular functions of long noncoding RNAs

open access: yesNature Cell Biology, 2019
Run-Wen Yao, Yang Wang, Ling-Ling Chen
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The landscape of long noncoding RNAs in the human transcriptome

open access: yesNature Genetics, 2015
M. Iyer   +18 more
semanticscholar   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Apoptotic metabolites synthesize and inherit unique <i>de novo</i> L2a/L2b RNAs to prevent virus infection. [PDF]

open access: yesBioact Mater
Li P   +14 more
europepmc   +1 more source

The Biogenesis, Functions, and Challenges of Circular RNAs.

open access: yesMolecules and Cells, 2018
Xiang Li, Li Yang, Ling-Ling Chen
semanticscholar   +1 more source

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