Results 251 to 260 of about 1,043,746 (362)

Interaction between Denatured DNA and Ribosomal RNA from Bacteria: Characterisation of DNA Sites Interacting with Ribosomal RNA at Room Temperature [PDF]

, 1968
M. Arcà, Ernesto Di Mauro, Laura Frontali, G. Tecce   +3 more
openalex   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Assembly of catalytic complexes from randomized oligonucleotides. [PDF]

Sci Adv
Han X, Müller UF.
europepmc   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

RNAs attack! [PDF]

Nature Reviews Genetics, 2013
openaire   +3 more sources

Revealing the role of U2AF1 in splicing regulation and chimeric RNA dynamics. [PDF]

Sci Rep
Khan S, Tang Y, Guo Y, Feng J, Wu H, Song Z, Zhang C, Qin F.   +7 more
europepmc   +1 more source

15 Decreased Incorporation of Uracil-2-C14 in the RNA Fraction of Mouse Fibroblast Cultures Grown with Pancreatic Diabetic Insulins [PDF]

, 1967
Claude Roy, Ronald W. Gotlin, Dennis Shapcott, Donough OʼBrien   +3 more
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Ring of resistance: Circular RNA Os-CircANK sequesters miR398b to counter rice blast resistance. [PDF]

Plant Cell
Ng PQ.
europepmc   +1 more source

ABSENCE OF RIBOSOMAL RNA SYNTHESIS IN THE ANUCLEOLATE MUTANT OF XENOPUS LAEVIS [PDF]

, 1964
Donald D. Brown, J. B. Gurdon
openalex   +1 more source