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TetraRNA, a tetra-class machine learning model for deciphering the coding potential derivation of RNA world. [PDF]
Bai H+7 more
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Nasopharyngeal carcinoma: a model cancer to understand tumor rejection. [PDF]
Nuovo GJ, Tili E, Croce CM.
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Photoaffinity enabled transcriptome-wide identification of splice modulating small molecule-RNA binding events in native cells. [PDF]
Shah R+9 more
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Deciphering the role of RNA in regulating CTCF's DNA binding affinity in leukemia cells. [PDF]
Hyle J+5 more
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The Co-Delivery of Natural Products and Small RNAs for Cancer Therapy: A Review. [PDF]
Wang X, Li S, Wang Z, Kang B, Yan H.
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RNA-dependent RNA polymerases in RNA silencing
Biological Chemistry, 2011Abstract RNA-dependent RNA polymerases (RdRPs) synthesize double-stranded RNAs that are processed into small RNAs and mediate gene silencing. Viral RdRPs and cellular RdRPs show little structural homology to each other. Cellular RdRPs play key roles in RNA silencing by producing complementary strands for target RNAs via Dicer-dependent and -
Yoshiko Maida, Kenkichi Masutomi
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RNA Editing with Viral RNA-Dependent RNA Polymerase
ACS Synthetic Biology, 2022RNA editing is currently attracting attention as a method for editing genetic information without injury to the genome. The most common approach to edit RNA sequences involves the induction of an A-to-I change by adenosine deaminase acting on RNA (ADAR). However, this method only allows point editing.
Shinzi Ogasawara, Ai Yamada
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RNA Libraries and RNA Recognitiona
Annals of the New York Academy of Sciences, 1996Random RNA libraries, consisting of > 10(13) unique sequences, contain molecules capable of specifically binding small molecule and protein ligands by noncovalent interaction. Successive steps of affinity purification and amplification allow the propagation and eventual isolation of specific binding molecules, called aptamers.
Hugh B. Nicholas+2 more
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