Results 361 to 370 of about 2,156,375 (387)

RNA-Based Drugs: From RNA Interference to Short Interfering RNAs

Current Pharmaceutical Biotechnology, 2004
RNA interference consists of a sequence specific post-transcriptional gene silencing phenomenon triggered by a double strand RNA molecule homologous to the silenced gene. The dsRNA is cleaved by DICER enzyme in small dsRNA pieces, named short interfering RNAs (siRNAs).
Poliseno L, Mercatanti A, Citti L, Rainaldi G   +3 more
openaire   +3 more sources

RNA TRANSPORT

Annual Review of Neuroscience, 1997
▪ Abstract  RNA molecules synthesized in the nucleus are transported to their sites of function throughout the eukaryotic cell by specific transport pathways. This review focuses on transport of messenger RNA, small nuclear RNA, ribosomal RNA, and transfer RNA between the nucleus and the cytoplasm.
S, Nakielny, U, Fischer, W M, Michael, G, Dreyfuss   +3 more
openaire   +2 more sources

Non-coding RNAs in disease: from mechanisms to therapeutics

Nature reviews genetics, 2023
Kinga Nemeth, R. Bayraktar, M. Ferracin, G. Calin   +3 more
semanticscholar   +1 more source

The biogenesis, biology and characterization of circular RNAs

Nature reviews genetics, 2019
L. Kristensen, M. S. Andersen, L. V. W. Stagsted, K. K. Ebbesen, T. B. Hansen, J. Kjems   +5 more
semanticscholar   +1 more source

Circular RNAs are a large class of animal RNAs with regulatory potency

Nature, 2013
Sebastian Memczak, Marvin Jens, Antigoni L Elefsinioti, F. Torti, Janna Krueger, Agnieszka Rybak, L. Maier, Sebastian D. Mackowiak, L. Gregersen, Mathias Munschauer, A. Loewer, U. Ziebold, M. Landthaler, C. Kocks, F. Noble, N. Rajewsky   +15 more
semanticscholar   +1 more source

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Nature, 2001
Sayda M. Elbashir, J. Harborth, Winfried Lendeckel, A. Yalçin, K. Weber, T. Tuschl   +5 more
semanticscholar   +1 more source

RNA processing

Current Opinion in Cell Biology, 1992
Significant progress has been made over the last year in our understanding of the roles that RNA-binding proteins play in pre-mRNA splicing, the components of the spliceosome and how these components relate to the mechanism of splicing. Of particular importance has been the sequence analysis of the first mammalian splicing factors and structural ...
openaire   +2 more sources

Biogenesis of small RNAs in animals

Nature reviews. Molecular cell biology, 2009
V. Kim, Jinju Han, M. Siomi
semanticscholar   +1 more source

The expanding regulatory mechanisms and cellular functions of circular RNAs

Nature reviews. Molecular cell biology, 2020
Ling-Ling Chen
semanticscholar   +1 more source

Non-coding RNAs in human disease

Nature reviews genetics, 2011
M. Esteller
semanticscholar   +1 more source