Results 181 to 190 of about 476,060 (306)
In the tripartite‐species model, Drosophila larvae stimulate lactate production through excreting digestion enzymes. S. marcescens population senses a cue of lactate and tends to diverge into virulent and reduced virulence subclusters with remarkable heterogeneity to metabolize carbon metabolism and counter colonization resistance, giving a fitness ...
Sheng Zhang+10 more
wiley +1 more source
The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction
Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang+8 more
wiley +1 more source
The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration. [PDF]
Jafar-Nejad P+13 more
europepmc +1 more source
Mutational spectrum analysis of RNase H(35) deficient Saccharomyces cerevisiae using fluorescence-based directed termination PCR [PDF]
J. Z. Chen
openalex +1 more source
Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim+12 more
wiley +1 more source
Homodimeric reverse transcriptases from Rous sarcoma virus mutated within the polymerase or RNase H active site of one subunit are active [PDF]
Susanne Werner, Birgitta M. Wöhrl
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Chronic social stress elevates oxytocin levels, leading to immunosuppression by enhancing regulatory T‐cell activity and promoting anti‐inflammatory macrophage polarization in the spleen. Blocking oxytocin signaling reverses these effects but worsens stress‐induced behavioral disorders and reduces survival rates. This highlights oxytocin's dual role in
Yi‐Shu Zhang+5 more
wiley +1 more source
Oral squamous cell carcinoma cells exhibit upregulated expression of GSDMD upon exposure to low‐dose cisplatin chemotherapy, which subsequently interacts with MMP14 through its N‐terminal domain, activating the epithelial‒mesenchymal transition (EMT) process and promoting the lymph node metastasis of oral squamous cell carcinoma.
Zixian Huang+9 more
wiley +1 more source
An RNase H-Like gene complements resistance to Bean common mosaic necrosis virus in Phaseolus vulgaris. [PDF]
Soler-Garzón A, Miklas PN.
europepmc +1 more source