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RNase H: Specificity, Mechanisms of Action, and Antiviral Target
2014The Ribonuclease (RNase) H is one of the four enzymes encoded by all retroviruses, including HIV. Its main activity is the hydrolysis of the RNA moiety in RNA-DNA hybrids. The RNase H ribonuclease is essential in the retroviral life cycle, since it generates and removes primers needed by the Reverse Transcriptase (RT) for initiation of DNA synthesis ...
John E. Kerrigan +3 more
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An RNase HâAssisted Fluorescent Biosensor for Aptamers
ChemBioChem, 2007Eun Gyeong Yang, Dae-Ro Ahn
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Molecular Mechanisms of Antisense Drugs: RNase H
Antisense and Nucleic Acid Drug Development, 1998openaire +2 more sources