Results 211 to 220 of about 1,979,759 (307)

GPATCH4 functions as a regulator of nucleolar R-loops in hepatocellular carcinoma cells. [PDF]

Nucleic Acids Res
Zhao YM, Jiang Y, Wang JZ, Cao S, Zhu H, Wang WK, Yu J, Liu J, Hui J.   +8 more
europepmc   +1 more source

Quorum Sensing Inhibits Type III‐A CRISPR‐Cas System Activity Through Repressing Positive Regulators SarA and ArcR in Staphylococcus Aureus

Advanced Science, EarlyView.
This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li, Yuanyue Tang, Xiaofei Li, Nina Molin Høyland‐Kroghsbo, Hanne Ingmer, Xinan Jiao, Qiuchun Li   +6 more
wiley   +1 more source

APEX2 RNA Proximity Labeling in Mammalian Cell Lines With Low Biotin Permeability. [PDF]

Bio Protoc
Tschan AB, Rai AK, Pelkmans L, McIntyre ABR.   +3 more
europepmc   +1 more source

A Phase Separation‐Assisted Pre‐Enrichment Method for Ultrasensitive Respiratory Virus Detection

Advanced Science, EarlyView.
Conventional biomarker enrichment lacks versatility and specificity. Phase separation‐assisted pre‐enrichment (PSAP) is introduced for concurrent antigen (47×) and RNA (44×) enrichment. Tenfold and fivefold lower detection limits for SARS‐CoV‐2 and Influenza, respectively, were achieved.
Yang Cao, Pui Ngan Lau, Alex W.H. Chin, Zhuolin He, Christina C. K. Au Yeung, Kehao Zeng, Haisong Lin, Leo L. M. Poon, Ho Cheung Shum   +8 more
wiley   +1 more source

Cytotoxicity and Binding to DNA, Lysozyme, Ribonuclease A, and Human Serum Albumin of the Diiodido Analog of Picoplatin. [PDF]

Inorg Chem
Ferraro G, Pracharova J, Gotte G, Massai L, Berecka M, Starha P, Messori L, Merlino A.   +7 more
europepmc   +1 more source

Crystal structure of the tRNA processing enzyme RNase PH from Aquifex aeolicus

Crystal structure of the tRNA processing enzyme RNase PH from Aquifex aeolicus
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

m6A Reader hnRNPA2B1 Modulates Late Pachytene Progression in Male Meiosis Through Post‐Transcriptional Control

Advanced Science, EarlyView.
As an m6A reader, hnRNPA2B1 predominantly regulates specific transcripts (e.g., Ep400, Rrs1) that are essential for chromosome organization and remodeling in an m6A‐dependent manner. Furthermore, it is demonstrated to interact with factors involved in mRNA processing and translation. This dual functionality is pivotal for ensuring the proper occurrence
Lisha Yin, Yuting Zhang, Bingqian Zhang, Jin Zhang, Mengneng Xiong, Nan Jiang, Jinxin Xiao, Huihui Gao, Wenjing Xiong, Xiaoli Wang, Fengli Wang, Shuiqiao Yuan   +11 more
wiley   +1 more source

Fast TV-PRO-seq: Accelerated and Streamlined Protocol for Timing RNA Polymerase Pausing. [PDF]

Bio Protoc
Zhang J, Liang Z, Sun M, Hebenstreit D, Zhang S.   +4 more
europepmc   +1 more source

ASO Therapy Targeting STAU2 to Inhibit Pancreatic Ductal Adenocarcinoma Progression and Metastasis by Regulating the PALLD‐Mediated EMT Signaling Pathway

Advanced Science, EarlyView.
This study identifies STAU2 as an oncogenic RNA‐binding protein (RBP) with elevated expression in pancreatic ductal adenocarcinoma (PDAC), where its high levels are significantly correlated with metastatic progression. It elucidates that STAU2 directly binds and regulates PALLD, while mediating the functional role of IQGAP1, thereby driving metastasis ...
Jiayu Ding, Hao Shen, Jiaying Ji, Jiaxing Li, Zhongrui Shi, Xuejiao Wang, Bangbang Li, Yi Hou, Wenjian Min, Chengliang Sun, Kai Yuan, Yasheng Zhu, Liping Wang, Shun‐Qing Liang, Wenbin Kuang, Xiao Wang, Peng Yang   +16 more
wiley   +1 more source

Structural Properties and Stability of Proteins in Dihydrolevoglucosenone/Water Mixtures. [PDF]

J Phys Chem B
Intze A, Polito R, Temperini ME, Incocciati A, Cappelletti C, Botta S, Ortolani M, Giliberti V, Piacentini R.   +8 more
europepmc   +1 more source