Results 241 to 250 of about 1,979,759 (307)

Integrative characterization of MYC RNA-binding function. [PDF]

Cell Genom
Li S, Wang Z, Wang X, Wang Y, Pattarayan D, Zhang Y, Nguyen P, Bhuniya A, Chen Y, Huang H, Huang Y, Wang L, Wang J, Li S, Zhang M, Liu Y, Lee N, Yang D.   +17 more
europepmc   +1 more source

Potential Application of a Water‐Soluble Fullerene C60 Decorated with Diethylene Glycol in Treatment of Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
A new ethoxyethanol derivative of iminofullerene, F2, is synthesized and labeled with 99mTc to produce 99mTc‐F2. In vitro, compound F2 inhibits the activation of primary mouse bone marrow‐derived macrophages stimulated with lipopolysaccharide. Moreover, 99mTc‐F2 is selectively enriched in the injured joints of mice. Inflammatory macrophages play a role
Rui He, Alyssa Costello, Yanjie Liu, Weicheng Wang, Zhichang Zhang, Quanjun Cui, Xinlin Yang   +6 more
wiley   +1 more source

Protocol for isolating nuclei from frozen fish heart tissue for single-cell genomic assays. [PDF]

STAR Protoc
Wei C, Jia R, Canário AVM, Chen L, Xu Q, Hu P.   +5 more
europepmc   +1 more source

Endogenously Triggered DNAzyme‐Based Nanostructures for Gene‐Combined Therapy

Advanced NanoBiomed Research, EarlyView.
DNAzymes show great promise for gene regulation and therapeutic use via controlled release triggered by endogenous factors. This review summarizes recent advances in designing and constructing nanoscale platforms enabling endogenously triggered release of DNAzyme.
Theoneste Muyizere, Julien Milon Essola, Eric Nyirimigabo, Janvier Mukiza, Jean Felix Mukerabigwi   +4 more
wiley   +1 more source

Metal‐Responsive Up‐Regulation of Bifunctional Disulfides for Suppressing Protein Misfolding and Promoting Oxidative Folding

Angewandte Chemie, EarlyView.
A stress‐responsive folding promotor was developed by conjugating metal‐binding ligands and a redox‐active disulfide. The oxidative strength of the bifunctional disulfide was enhanced by metal coordination, inhibiting protein misfolding and up‐regulating the oxidative folding capacity under metal stress.
Keita Mori, Tsubura Kuramochi, Motonori Matsusaki, Yuki Hashiguchi, Masaki Okumura, Tomohide Saio, Yoshiaki Furukawa, Kenta Arai, Takahiro Muraoka   +8 more
wiley   +2 more sources

Dynamic Transcription Machineries in Protocells. [PDF]

J Am Chem Soc
Dong J, Xia F, Huang F, Willner I.
europepmc   +1 more source

Design and Application of Piezoelectric Conductive Smart Scaffold for Noninvasive Neural Tissue Regeneration via Custom‐Made In Vitro Mechano‐Stimulator

Advanced NanoBiomed Research, EarlyView.
Schematic illustration showing the design of the developed invitro mechano stimulator (IMS) and the electrospun nanofiber‐based piezoelectric and conductive nerve conduit (PCNC) that can self‐generate electrical stimulations analogous to neural tissues. IMS provided vital electrical cues for the neural cells to attach, align and proliferate on the PCNC
Afeesh Rajan Unnithan, Vignesh Krishnamoorthi Kaliannagounder, Nagamalleswara Rao Alluri, Chan Hee Park, Pandiyarasan Veluswamy, Arathyram Ramachandra Kurup Sasikala   +5 more
wiley   +1 more source

FASTKD5 processes mitochondrial pre-mRNAs at noncanonical cleavage sites. [PDF]

Nucleic Acids Res
Antonicka H, Vučković A, Weraarpachai W, Hong S, Brischigliaro M, Ahn A, Barrientos A, Hillen HS, Shoubridge EA.   +8 more
europepmc   +1 more source

Nanoparticles Functionalized with Polymer Brushes for Gene Delivery

Advanced NanoBiomed Research, EarlyView.
The engineering of the next generation gene delivery vectors requires the precise control of the architecture and physicochemical interactions controlling the transport, targeting, uptake, and release of nucleic acid materials to targeted cells. Polymer brush‐functionalized nanomaterials offer unprecedented control over such design and properties, and ...
Carlos E. Neri‐Cruz, Julien E. Gautrot
wiley   +1 more source

Fusion of SARS-CoV-2 neutralizing LCB1 peptide with Bacillus amyloliquefaciens RNase improves antiviral efficacy. [PDF]

Sci Rep
Kostin NN, Bobik TV, Konovalova EV, Kocharovskaya MV, Simonova MA, Rushkevich NY, Mokrushina YA, Skryabin GA, Kalinin RS, Kovalchuk SI, Ziganshin RH, Kaluzhskiy LA, Gnedenko OV, Yablokov EO, Ivanov AS, Chernov AS, Kazakov VA, Khokhlova ON, Murashev AN, Hong S, Shramova EI, Schulga AA, Lyukmanova EN, Kirpichnikov MP, Smirnov IV, Belogurov AA, Rubtsov YP, Stepanov AV, Zhang H, Gabibov AG, Deyev SM.   +30 more
europepmc   +1 more source