Results 251 to 260 of about 299,739 (289)

Progress in Molecular Imprinting—From Inhibition of Enzymatic Activity to Regulation of Cellular Pathways

Medicinal Research Reviews, EarlyView.
ABSTRACT Molecular imprinting is a very powerful tool in life science. The research areas benefiting from a wide range of capabilities of molecularly imprinted polymeric nanoparticles (nanoMIPs) include sample preparation, extraction, sensing/detection, diagnostics, and drug delivery.
Milada Vodova, Jaroslava Bezdekova, Marketa Vaculovicova   +2 more
wiley   +1 more source

Current Analytical Strategies for mRNA-Based Therapeutics. [PDF]

Molecules
Camperi J, Chatla K, Freund E, Galan C, Lippold S, Guilbaud A.   +5 more
europepmc   +1 more source

Navigating Uncertainties in RT-qPCR and Infectivity Assessment of Norovirus. [PDF]

Food Environ Virol
Mirmahdi RS, Dicker SL, Yusuf NG, Montazeri N.   +3 more
europepmc   +1 more source

The HBV variant CpF97L supports the secretion of pgRNA-containing virions at a level much greater than WT HBV. [PDF]

J Virol
Kissi-Twum AA, Pionek K, Loeb DD.
europepmc   +1 more source

Comprehensive nucleoside analysis of archaeal RNA modification profiles reveals an m⁷G in the conserved P loop of 23S rRNA. [PDF]

Cell Rep
Tsai YL, Wolf EJ, Fluke KA, Fuchs RT, Dai N, Johnson SR, Sun Z, Elkins L, Burkhart BW, Santangelo TJ, Corrêa IR.   +10 more
europepmc   +1 more source

Characterisation and analysis of mRNA critical quality attributes using liquid chromatography based methods.

J Chromatogr A
Webb ALJ, Welbourne EN, Evans CA, Dickman MJ.   +3 more
europepmc   +1 more source

pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing

Biomacromolecules, 2015
Intracellularly-acting therapeutic proteins are considered promising alternatives for the treatment of various diseases. Major limitations of their application are low efficiency of intracellular delivery and possible reduction of protein activity during derivatization.
Xiaowen Liu, Peng Zhang, Dongsheng He, Wolfgang Rödl, Tobias Preiß, Joachim O. Rädler, Ernst Wagner, Ulrich Lächelt   +7 more
openalex   +3 more sources

RNase PH catalyzes a synthetic reaction, the addition of nucleotides to the 3′ end of RNA

Biochimie, 1990
Escherichia coli RNase PH is a phosphate-dependent exoribonuclease that has been implicated in the 3' processing of tRNA precursors. It degrades RNA chains in a phosphorolytic manner releasing nucleoside diphosphates as products. Here we show that RNase PH also catalyzes a synthetic reaction, the addition of nucleotides to the 3' termini of RNA ...
K A Ost, Murray P. Deutscher
openalex   +4 more sources

[68] Preparation of bacterial DNA by the phenol-pH 9-RNases method

, 1967
Publisher Summary This chapter describes the method for the extraction of DNA from bacterial cells using phenol. Phenol treatment is considered one of the most effective methods for deproteinization. Whereas a neutral or acidic buffer (pH 5-7) extracts RNA into aqueous phase, rather than DNA from bacterial cells, in phenol treatment slightly alkaline
Kin‐ichiro Miura
openalex   +3 more sources