Results 251 to 260 of about 1,979,759 (307)

Engineering of novel DNA polymerase variants for single enzyme quantitative multiplex reverse transcription-PCR. [PDF]

Sci Rep
Huber LB, Marchand V, Somtürk M, Müller S, Marx A.   +4 more
europepmc   +1 more source

Intrazellulärer Transport nativer Proteine durch Bioreversible Arginin‐Modifikation (BioRAM) primärer Aminogruppen

Angewandte Chemie, EarlyView.
Die Bioreversible Arginin‐Modifikation aminhaltiger Proteinreste (BioRAM) ermöglicht eine serumkompatible, leicht zugängliche und effiziente Einschleusung nativer Proteine in lebende Zellen. In Kombination mit zellpenetrierenden Peptid‐Additiven führt BioRAM zu nanomolarer intrazellulären RNase‐A‐Aktivität und erlaubt so den zellulären Transport ...
Jonathan Franke, Jan Vincent V. Arafiles, Christian Leis, Christian P. R. Hackenberger   +3 more
wiley   +1 more source

Design, Synthesis and Biological Evaluation of 3-Hydrazonoindolin-2-one Derivatives as Novel HIV-1 RNase H Inhibitors. [PDF]

Molecules
Zhang Y, Wang R, Bu Y, Corona A, Dettori L, Tramontano E, Pannecouque C, De Clercq E, Wang S, Meng G, Chen FE.   +10 more
europepmc   +1 more source

Intracellular Delivery of Native Proteins by BioReversible Arginine Modification (BioRAM) on Amino Groups

Angewandte Chemie International Edition, EarlyView.
Bioreversible Arginine Modification of amine‐containing protein residues (termed BioRAM) allows the serum‐compatible, readily accessible, and efficient delivery of native proteins into live cells. Combined with cell‐penetrating peptide (CPP) additives, BioRAM results in intracellular RNase A activity at nanomolar concentrations, thus enabling the ...
Jonathan Franke, Jan Vincent V. Arafiles, Christian Leis, Christian P. R. Hackenberger   +3 more
wiley   +1 more source

An atlas of RNA-dependent proteins in cell division reveals the riboregulation of mitotic protein-protein interactions. [PDF]

Nat Commun
Rajagopal V, Seiler J, Nasa I, Cantarella S, Theiss J, Herget F, Kaifer B, Klostermann M, Will R, Schneider M, Helm D, König J, Zarnack K, Diederichs S, Kettenbach AN, Caudron-Herger M.   +15 more
europepmc   +1 more source

Articoli Schwarz(strand_seclection) / Grishok(stRNA&RNAi) / Han(microprocessor) [PDF]

, 2012
Danielli, Alberto
core  

Restoration of human tooth enamel

BMEMat, EarlyView.
Human tooth enamel has remarkable properties but lacks self‐repair ability. Existing restorative materials cannot fully replicate enamel's microstructure and function, resulting in low restorative efficiency. This review summarizes the formation process and characteristics of enamel, and current restorative materials and future research directions are ...
Hanlin Liu, Bo Li, Mingrui Gao, Yangbei Li, Xiuyi Yang, Fengshi Li, Zhi Cai, Yi Liu, Shaojia Liu, Hewei Zhao, Lin Guo   +10 more
wiley   +1 more source

Chemical nucleases are a robust alternative for RNase H cleavage of human ribosomal RNA. [PDF]

PLoS One
Wesseling H, Krug D, Wehrheim M, Göbel MW, Kaiser S.   +4 more
europepmc   +1 more source

The effect of sodium nitroprusside in scaffolds for synergetic gas‐photothermal therapy of osteosarcoma

BMEMat, EarlyView.
The PCLA‐SNP scaffolds can produce photothermal agents in situ under ultraviolet radiation. Then, the scaffold can release nitric oxide gas spontaneously and generate hyperthermia under near‐infrared laser to enhance ablation of bone tumors. Furthermore, the calcium and iron ions released from PCLA‐SNP scaffolds can accelerate bone regeneration ...
Shaojie Dong, Yuwei Zhang, Yukun Mei, Changjie Sun, Xingge Yu, Mazaher Gholipourmalekabadi, Kaili Lin, Lin Niu, Li Zhao, Changyong Yuan   +9 more
wiley   +1 more source

2'-O-methylation and N6-methyladenosine enhance the oral delivery of small RNAs in mice. [PDF]

Mol Ther Nucleic Acids
Guo S, Li Z, Li X, Liang Z, Zhao D, Sun N, Liu J, Wang X, Mei S, Qiao X, Jiang C.   +10 more
europepmc   +1 more source