Results 261 to 270 of about 1,979,759 (307)

Use of LC‐MS to characterize host cell protein removal during depth filtration

Biotechnology Progress, EarlyView.
Abstract The removal of host cell proteins (HCPs) is crucial in biopharmaceutical production, as residual impurities can impact product safety and efficacy. While a number of studies have demonstrated that depth filtration can provide significant HCP removal, there is little information on its effectiveness in removing specific HCPs.
Liang‐Kai Chu, Ehsan Espah Borujeni, Xuankuo Xu, Andrew L. Zydney   +3 more
wiley   +1 more source

The ribonuclease RNase T2 mediates selective autophagy of ribosomes induced by starvation in Saccharomyces cerevisiae. [PDF]

J Biol Chem
Minami A, Nishi K, Yamada R, Jinnai G, Shima H, Oishi S, Akagawa H, Aono T, Hidaka M, Masaki H, Kuzuyama T, Noda Y, Ogawa T.   +12 more
europepmc   +1 more source

N6‐methyladenosine‐regulated exosome biogenesis orchestrates an immunosuppressive pre‐metastatic niche in gastric cancer peritoneal metastasis

Cancer Communications, EarlyView.
Abstract Background Gastric cancer peritoneal metastasis is clinically challenging, given the limited treatment options and poor prognosis. The molecular mechanisms that precede gastric cancer peritoneal metastasis, known as the pre‐metastatic niche (PMN), and its relationship with N6‐methyladenosine (m6A) modification remain unclear.
Song Li, Jianyuan Zhou, Shuang Wang, Qian Yang, Shulun Nie, Chunwang Ji, Xue Zhang, Shuhan Li, Xuanyu Zhou, Jiahui Chu, Xuehui Wu, Jianqiao Jiao, Ruitao Xu, Qian Xu, Miao Huang, Qiushi Wang, Liliang Dou, Qinqin Hu, Fan Jiang, Xin Dai, Zhaodi Nan, Xinyu Song, Di Zhang, Lian Liu   +23 more
wiley   +1 more source

Protocol to perform polysome profiling in primary differentiating murine adipocytes. [PDF]

STAR Protoc
De Siqueira MK, Nouhi Z, Zhao Y, Wang S, Xiao X, Yang X, Hulea L, Villanueva CJ.   +7 more
europepmc   +1 more source

Protocol for evaluating compound uptake and RNase L co-localization in live cells using fluorescence-based binding, competition assay, and confocal microscopy. [PDF]

STAR Protoc
Khaskia E, Benhamou RI.
europepmc   +1 more source

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis. [PDF]

FEBS Lett
Gilet L, Leroy M, Maes A, Condon C, Braun F.   +4 more
europepmc   +1 more source

Cobra Three-Finger Toxins Interact with RNA and DNA: Nucleic Acids as Their Putative Biological Targets. [PDF]

Int J Mol Sci
Osipov AV, Starkov VG, Tsetlin VI, Utkin YN.   +3 more
europepmc   +1 more source

A Robust Expression and Purification Protocol for the Production of the La Domain of Human LARP6. [PDF]

ACS Omega
Gordon BH, Blackford N, Silvers R.
europepmc   +1 more source

Innate immune responses to lysosomal nucleic acid stress. [PDF]

J Biochem
Miyake K, Shibata T, Sato R, Fukui R.
europepmc   +1 more source