A study of ribonuclease activity in venom of vietnam cobra
Background Ribonuclease (RNase) is one of the few toxic proteins that are present constantly in snake venoms of all types. However, to date this RNase is still poorly studied in comparison not only with other toxic proteins of snake venom, but also with ...
Thiet Van Nguyen, A. V. Osipov
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Dual miRNases for Triple Incision of miRNA Target: Design Concept and Catalytic Performance
Irreversible destruction of disease-associated regulatory RNA sequences offers exciting opportunities for safe and powerful therapeutic interventions against human pathophysiology.
Olga Patutina +6 more
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Cationic poly(amidoamine) promotes cytosolic delivery of bovine RNase A in melanoma cells, while maintaining its cellular toxicity [PDF]
Ribonucleases are known to cleave ribonucleic acids, inducing cell death. RNase A, a member of the ribonuclease family, generally displayed poor in vitro activity. This has been attributed to factors such as low intracellular delivery.
Akinc +60 more
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First biochemical characterization of a novel ribonuclease from wild mushroom Amanita hemibapha [PDF]
A 45-kDa ribonuclease (RNase) was purified from dried fruiting bodies of the wild mushroom Amanita hemibapha. It was adsorbed on DEAE-cellulose, S-sepharose, and finally purified on Superdex 75. The RNase exhibited maximal RNase activity at pH 5 and in a
Bo Wang +4 more
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Effect of native gastric mucus on in vivo hybridization therapies directed at Helicobacter pylori [PDF]
Helicobacter pylori infects more than 50% of the worldwide population. It is mostly found deep in the gastric mucus lining of the stomach, being a major cause of peptic ulcers and gastric adenocarcinoma. To face the increasing resistance of H.
Azevedo, Nuno F +13 more
core +9 more sources
Two glycoproteidic acid RNases (RNase I and RNase II) were obtained and purified from the seeds of Dactylis glomerata by extraction with acetate buffer, fractionation with ammonium sulfate, ion-exchange chromatography on DEAE-cellulose, DEAE-Sphadex ...
Janina Wiśniowska +1 more
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A multifunctional ribonuclease A-conjugated carbon dot cluster nanosystem for synchronous cancer imaging and therapy [PDF]
Carbon dots exhibit great potential in applications such as molecular imaging and in vivo molecular tracking. However, how to enhance fluorescence intensity of carbon dots has become a great challenge.
Chao Li +7 more
core +2 more sources
Dependence of ethanol effects on protein charges [PDF]
Ethanol is used as a conventional disinfectant solution. It is highly effective against enveloped viruses due to its effects on virus membranes. It also confers inactivation of non-enveloped viruses, which can be ascribed to conformational changes or ...
Arakawa Tsutomu +3 more
core +1 more source
Refolding of ribonuclease A in vitro and conformational characterization by spectrofluorimetry
Ribonuclease A (RNase A) was employed as a model protein to understand the formation of correct three-dimensional structure in the refolding of recombinant proteins in vitro.
TAN Pei-sheng +4 more
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Effects of rnase iii rncs gene deletion on stress response, biofilm formation and virulence of listeria monocytogenes [PDF]
The ribonuclease III (RNase III) is an important enzyme system that regulates non-coding RNA (ncRNA) levels. In this study, LM-ΔrncS gene deletion strain was investigated by gene overlap extension PCR (SOE-PCR) and homologous recombination techniques ...
Lixia WANG +9 more
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