Results 31 to 40 of about 315,883 (294)

A study of ribonuclease activity in venom of vietnam cobra

open access: yesJournal of Animal Science and Technology, 2017
Background Ribonuclease (RNase) is one of the few toxic proteins that are present constantly in snake venoms of all types. However, to date this RNase is still poorly studied in comparison not only with other toxic proteins of snake venom, but also with ...
Thiet Van Nguyen, A. V. Osipov
doaj   +1 more source

Dual miRNases for Triple Incision of miRNA Target: Design Concept and Catalytic Performance

open access: yesMolecules, 2020
Irreversible destruction of disease-associated regulatory RNA sequences offers exciting opportunities for safe and powerful therapeutic interventions against human pathophysiology.
Olga Patutina   +6 more
doaj   +1 more source

Cationic poly(amidoamine) promotes cytosolic delivery of bovine RNase A in melanoma cells, while maintaining its cellular toxicity [PDF]

open access: yes, 2015
Ribonucleases are known to cleave ribonucleic acids, inducing cell death. RNase A, a member of the ribonuclease family, generally displayed poor in vitro activity. This has been attributed to factors such as low intracellular delivery.
Akinc   +60 more
core   +1 more source

First biochemical characterization of a novel ribonuclease from wild mushroom Amanita hemibapha [PDF]

open access: yes, 2012
A 45-kDa ribonuclease (RNase) was purified from dried fruiting bodies of the wild mushroom Amanita hemibapha. It was adsorbed on DEAE-cellulose, S-sepharose, and finally purified on Superdex 75. The RNase exhibited maximal RNase activity at pH 5 and in a
Bo Wang   +4 more
core   +1 more source

Effect of native gastric mucus on in vivo hybridization therapies directed at Helicobacter pylori [PDF]

open access: yes, 2015
Helicobacter pylori infects more than 50% of the worldwide population. It is mostly found deep in the gastric mucus lining of the stomach, being a major cause of peptic ulcers and gastric adenocarcinoma. To face the increasing resistance of H.
Azevedo, Nuno F   +13 more
core   +9 more sources

Two acid RNases from Dactylis glomerata seeds. Purification, properties and effect of polyamines and lectins on their activity

open access: yesActa Societatis Botanicorum Poloniae, 2014
Two glycoproteidic acid RNases (RNase I and RNase II) were obtained and purified from the seeds of Dactylis glomerata by extraction with acetate buffer, fractionation with ammonium sulfate, ion-exchange chromatography on DEAE-cellulose, DEAE-Sphadex ...
Janina Wiśniowska   +1 more
doaj   +1 more source

A multifunctional ribonuclease A-conjugated carbon dot cluster nanosystem for synchronous cancer imaging and therapy [PDF]

open access: yes, 2014
Carbon dots exhibit great potential in applications such as molecular imaging and in vivo molecular tracking. However, how to enhance fluorescence intensity of carbon dots has become a great challenge.
Chao Li   +7 more
core   +2 more sources

Dependence of ethanol effects on protein charges [PDF]

open access: yes, 2014
Ethanol is used as a conventional disinfectant solution. It is highly effective against enveloped viruses due to its effects on virus membranes. It also confers inactivation of non-enveloped viruses, which can be ascribed to conformational changes or ...
Arakawa Tsutomu   +3 more
core   +1 more source

Refolding of ribonuclease A in vitro and conformational characterization by spectrofluorimetry

open access: yes浙江大学学报. 农业与生命科学版, 2006
Ribonuclease A (RNase A) was employed as a model protein to understand the formation of correct three-dimensional structure in the refolding of recombinant proteins in vitro.
TAN Pei-sheng   +4 more
doaj   +1 more source

Effects of rnase iii rncs gene deletion on stress response, biofilm formation and virulence of listeria monocytogenes [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2019
The ribonuclease III (RNase III) is an important enzyme system that regulates non-coding RNA (ncRNA) levels. In this study, LM-ΔrncS gene deletion strain was investigated by gene overlap extension PCR (SOE-PCR) and homologous recombination techniques ...
Lixia WANG   +9 more
doaj   +1 more source

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