Results 41 to 50 of about 2,117,519 (243)
Proposal for the Integration of Health and Safety into the Design of Road Projects with BIM
Buildings, 2022 The high number of accidents in the construction sector makes the concept of prevention through design (PtD), which starts with the integration of an occupational risk assessment in this phase, increasingly important.
Darío Collado-Mariscal +3 more
doaj +1 more source
Nature Conservation Research: Заповедная наука, 2020 Protected Areas in Borneo retain some of the best examples of biodiversity and are the last refuge for wildlife conservation in tropical rainforests. Therefore, understanding the species richness and composition in increasingly fragmented Protected Areas
Jayasilan Mohd-Azlan +6 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi +9 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
, 1995 copyright UK Data Service and data collection copyright owner.Road accident statistics are collected from information about personal injury road accidents and their consequent casualties, to a common national standard.
Department of Transport, Road Accident Statistics Branch
core +2 more sources
, 2015 copyright UK Data Service and data collection copyright owner.Road accident statistics are collected from information about personal injury road accidents and their consequent casualties, to a common national standard.
Department for Transport, Road Accident Statistics Branch
core +3 more sources
GIS TECHNIQUES FOR ASSESSING THE LINK BETWEEN HUMAN ACCESSIBILITY AND TERRITORIAL DISTRIBUTION OF THE POPULATION IN HUNEDOARA COUNTY [PDF]
Studia Universitatis Babeş-Bolyai: Geographia, 2014 GIS Techniques for Assessing the Link between Human Accessibility and Territorial Distribution of the Population in Hunedoara County. The accessibility of an area has a very important role in the territorial distribution of the population in an area.
R. COSTACHE, C. POPESCU, A. ȘTEFAN
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source