Results 61 to 70 of about 4,722,044 (303)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Prioritization of Factors Influencing Customer’s Choice of Land Freight Transportation Mode (Road and Railway) [PDF]

International Journal of Railway Research
The decision-making process of customers choosing a product or service is complex and dependent on many factors. These factors do not remain unchanged, and customers may change their behavior over time.
Akram Rostamkhani, Milad Alizadeh Galdiani, Mohammadreza Rezazadeh, Seyed Ali Mosayebi   +3 more
doaj  

Modelling indirect tensile strength of warm mix asphalt with variable reclaimed asphalt pavement (RAP) content [PDF]

Дороги і мости
Introduction. There is a world-wide trend to also increase the sustainability of the road sector. The growing use of various industrial by-products, together with economical and eco-friendly construction and maintenance techniques can be observed in many
Ali Saleh, László Gáspár
doaj   +1 more source

Prioritization of Road Network Construction in Bacan Island of North Maluku Province [PDF]

, 2013
Bacan Island, located in South Halmahera, North Maluku Province, is a potential region with a variety of important sectors, such as plantations, fisheries, mining, tourism, industry and trade.
Bowoputro, H. (Hendi), Djakfar, L. (Ludfi), Mashudman, M. (Mashudman)   +2 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Problematic issues of ensuring the quality of road construction materials and products in the context of their certification in Ukraine according to DSTU EN ISO/IEC 17065:2019 and the law of Ukraine “On the provision of construction products on the market [PDF]

Дороги і мости
Introduction. The article examines the importance of certification of road construction materials as one of the main tools for ensuring their quality. Problems.
Andrii Skrypnyk, Mariia Yachnyk, Volodymyr Kaskiv, Volodymyr Zelenovsky   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Analysis of international experience in implementing “Design-Build” and “Design-Build-Operate” contracts [PDF]

Дороги і мости
Introduction. The article examines the international experience of implementing large infrastructure projects in various countries using the “Design-Build” and “Design-Build-Operate” methods.
Viktor Komar
doaj   +1 more source

Assessment of Road Rehabilitation in Ibadan, Nigeria

Indonesian Journal of Geography, 2020
The study examined road rehabilitation in Ibadan North East Local Government of Oyo State, Nigeria. The data used in this study was obtained from both primary and secondary sources.
Adewale Yoade, Samson Olaitan Olanrewaju, Sesan Adeniyi Adeyemi   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source