Results 81 to 90 of about 1,777,837 (318)
Economically Optimal Road Subnetwork
The paper deals with the following situation: An area is served by a transportation network, usually the road one. The current quality of the network is not satisfactory for the owner (e.g.
Anna Cerna, Jan Cerny, Vladimir Pribyl
doaj +1 more source
Key questions for road investment and spending
This report has been produced by the Road Investment Scrutiny Panel – an assembled group of senior professionals supported by funding from the Rees Jeffreys Road Fund.Roads are the arteries of economic and social prosperity.
Road Investment Scrutiny Panel
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Development of Intelligent Transport Systems in Russia: problems and solutions. New stage
The situation with the development of intelligent transport systems (ITS) in Russia is characterized. The main problems of the development of ITS in our country are considered.
A. I. Solodkiy
doaj +1 more source
copyright UK Data Service and data collection copyright owner.Road accident statistics are collected from information about personal injury road accidents and their consequent casualties, to a common national standard.
Department of the Environment, Transport and the Regions, Road Accidents Branch
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
copyright UK Data Service and data collection copyright owner.Road accident statistics are collected from information about personal injury road accidents and their consequent casualties, to a common national standard.
Department of the Environment, Transport and the Regions, Road Accidents Branch
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Background and objective: Traffic accidents are a contributing factor to any loss of life, property, or services. It occurs when a vehicle collides with another vehicle or object.
Muhsen Kamal Yasen
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source

