Results 61 to 70 of about 262,162 (255)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
FireThe risk of wildfires is increasing due to high temperatures and dry weather conditions caused by climate change. Outbreaks and spread of wildfires are usually conditioned by weather, topography, and fuel characteristics.
Youn Yeo-Chang +3 more
doaj +1 more source
An elimination method for isolated meshes in a road network considering stroke edge feature.
PLoS ONE, 2020 The road network is the skeletal element of topographic maps at different scales. In general, urban roads are connected by road segments, thus forming a series of road meshes.
Chengming Li +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Spatial Analysis and Identification of Erosion and Sediment Hot-Spots Along Zagros Forest Roads [PDF]
علوم آب و خاکIn the present study, the Road Sediment Delivery Model (SEDMODL) and Geographic Information System (GIS) were utilized to estimate the average annual sedimentation caused by the forest road network in the oak forests in the west of Iran, Chaharmahal and ...
S. Yousefi +3 more
doaj
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
DIFFERENTIATIONS OF ROAD INFRASTRUCTURE AND THE DEVELOPMENT OF POLISH ENTERPRISES IN 2012-2021 [PDF]
Annals of the Polish Association of Agricultural and Agribusiness EconomistsThis work presents the relationship between road infrastructure and the development of enterprises in Poland. The aim of the study was to assess the differences in the density of the hard surface road network and the development of enterprises, as well ...
Irena Kropsz-Wydra, Izabela Kurtyka
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Procedia Environmental Sciences, 2011 AbstractThe study attempt to define an anthropogenic pressure index (IA) on the basis of the data, available for Upper Silesian Metropolitan Union districts. The volume of generated waste, population density and road network density, were taken into account to determine this parameter.
Absalon, Damian, Ślesak, Barbara
openaire +3 more sources
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source