Results 31 to 40 of about 2,046,097 (305)

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker   +7 more
wiley   +1 more source

The Challenges and Obstacles of Post-Disaster Road Infrastructure Reconstruction in the Pre-Construction Phase [PDF]

open access: yes, 2015
Purpose The reconstruction of road infrastructure in the post-disaster context require different approach when compared with road projects in the normal development context.
Amaratunga, Dilanthi   +2 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Guidelines for the Use of Synthetic Fluid Dust Control Palliatives on Unpaved Roads [PDF]

open access: yes, 2017
The amount of small soil particles, dust, lost from typical unpaved roads to fugitive dust is staggering. A 1 km stretch of unpaved road can contribute over 2400 kg of dust to the atmosphere (4.2 ton/mile) in a typical 3-month summer season.
Barnes, David, Connor, Billy
core  

Presumptions—The Uniform Rules in the Federal Courts [PDF]

open access: yes, 1964
Emerging heavy duty vehicle control systems increasingly rely on advance knowledge of the road topography, described by the longitudinal road grade. Highway road grade profiles are restricted by road design specifications to be piecewise affine.
Gattami, Ather   +2 more
core   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

A Monolayer Leaky Integrate‐and‐Fire Neuron for 2D Memristive Neuromorphic Networks

open access: yesAdvanced Electronic Materials, 2020
2D material based memristors have exhibited superior performance as artificial synapses for neuromorphic computing. However, 2D artificial neurons as have note been exploited as an indispensable computational element owing to the rich dynamics of neurons,
Song Hao   +6 more
doaj   +1 more source

Influencing driver behaviour through road marking [PDF]

open access: yes, 2005
This paper will describe how road marking can be used to influence driver behaviour in order to improve road safety and traffic flows. Extensive use will be made of examples from recent research undertaken by the authors on overtaking lane design, speed ...
Baas, Peter H., Charlton, Samuel G.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Impact of Perceptual Road Markings on Driving Behavior in Horizontal Curves: A Driving Simulator Study

open access: yesApplied Sciences
Horizontal curves have been a significant safety concern on roads for years, often resulting in a high incidence of crashes. A European Road Safety Observatory report indicated that 53% of road crashes in the EU in 2020 occurred on rural roads, mainly ...
Ali Pirdavani   +3 more
doaj   +1 more source

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