Results 81 to 90 of about 2,046,097 (305)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Age Determination of Blood-Stained Fingerprints Using Visible Wavelength Reflectance Hyperspectral Imaging

Journal of Imaging, 2018
The ability to establish the exact time a crime was committed is one of the fundamental aims of forensic science. The analysis of recovered evidence can provide information to assist in age determination, such as blood, which is one of the most commonly ...
Samuel Cadd, Bo Li, Peter Beveridge, William T. O'Hare, Meez Islam   +4 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Research on Primary Shielding Calculation Source Generation Codes

EPJ Web of Conferences, 2017
Primary Shielding Calculation (PSC) plays an important role in reactor shielding design and analysis. In order to facilitate PSC, a source generation code is developed to generate cumulative distribution functions (CDF) for the source particle sample ...
Zheng Zheng, Mei Qiliang, Li Hui, Shangguan Danhua, Zhang Guangchun   +4 more
doaj   +1 more source

Economic Standards for Pedestrian Areas for Disabled People: Results from Observation Work [PDF]

, 1988
1.1.1 The Institute for Transport Studies was invited by the Transport and Road Research Laboratory to submit a research proposal, with costs, aimed at establishing suitable "Ergonomic Standards for Pedestrian Areas for Disabled People".
Berrett, B., Leake, G., May, A.D., Parry, T., Whelan, J.   +4 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Comparison of H∞ and μ-synthesis Control Design for Quarter Car Active Suspension System using Simulink [PDF]

, 2020
To improve road dealing with and passenger consolation of a vehicle, a suspension system is supplied. An active suspension system is taken into consideration better than the passive suspension system.
Jibril, Mustefa
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Detection of Geometric Risk Factors Affecting Head-On Collisions through Multiple Logistic Regression: Improving Two-Way Rural Road Design via 2+1 Road Adaptation. [PDF]

Int J Environ Res Public Health, 2021
Cáceres L, Fernández MA, Gordaliza A, Molinero A.   +3 more
europepmc   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source