Results 91 to 100 of about 5,688,954 (256)

Road Accident Data, 1994

, 1995
copyright UK Data Service and data collection copyright owner.Road accident statistics are collected from information about personal injury road accidents and their consequent casualties, to a common national standard.
Department of Transport, Road Accident Statistics Branch
core   +4 more sources

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

New Microsurfacing Specifications Improve Cold-Temperature Performance of Asphalt Pavements [PDF]

, 2015
This 2-page fact sheet provides information about microsurfacing and recent research to enhance its effectiveness in colder climates.Transportation Engineering and Road Research Alliance (TERRA). (2015).
Transportation Engineering and Road Research Alliance (TERRA)
core  

The influence of compaction frequency on the skeleton characteristics of asphalt mixtures

Journal of Highway and Transportation Research and Development
In order to understand the influence of compaction energy on the skeletal structure of dense-graded asphalt mixtures, it is essential to establish a stable skeletal framework.
Yichong Chen, Xianglin Lu, Junlin Zhou, Leizhou Cai, Cansheng Wang, Cheng Lu   +5 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Curb Detection and Mapping via Robust Iterative Gaussian Process Regression

Journal of Highway and Transportation Research and Development
Curb detection and mapping are of great importance to ensure the safety and efficiency of intelligent vehicles. However, it remains challenging because shape estimation under noise and outliers is not well addressed in real traffic scenarios.
Di Wang, Si Chen, Zhenni Ma, Jiajia Shi, Fuchun Zhang   +4 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Highway foundation treatment techniques in permafrost regions of the Qinghai-Tibet Plateau: Current practices and future trends

Journal of Highway and Transportation Research and Development
In the context of global warming, existing highways in the permafrost regions of the Qinghai-Tibet Plateau are facing multiple challenges, including surface settlement, roadside water accumulation, groundwater saturation, thickening of melting ...
Bo Tian
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Implementation of New Technologies [PDF]

, 2008
This 2-page fact sheet provides information about three technologies and their implementation in Minnesota: Intelligent Compaction (IC), the Dynamic Cone Penetrometer (DCP), and Ground Penetrating Radar (GPR).Transportation Engineering and Road Research ...
Transportation Engineering and Road Research Alliance (TERRA)
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