Results 21 to 30 of about 5,688,954 (256)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Low-Cost Engineering Infrastructure Safety Improvements [PDF]
, 2011 This 2-page fact sheet describes some low-cost, effective engineering safety improvements that DOTs can integrate into their road building and restoration programs, particularly regarding road/lane departures and intersection crashes.Transportation ...
Transportation Engineering and Road Research Alliance (TERRA)
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Fly ash for sustainable roads: A comprehensive review on mechanisms and performance optimization
Journal of Road EngineeringFly ash (FA), a major solid waste from coal-fired industries, represents a critical pathway for the green disposal of bulk solid waste and the low-carbon construction of transportation infrastructure, holding significant strategic importance.
Yingxin Hui +6 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Geotechnical Problems Of The Foundation Of Road Embankments By The Bridge Structures
Studia Geotechnica et Mechanica, 2019 This work presents the geotechnical problems occurring in the interaction area between road embankments and the bridge structures in case a subsoil characterised by complex and complicated geological and engineering conditions. These significant problems
Batog Andrzej, Stilger-Szydło Elżbieta
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2010 This 2-page fact sheet provides information about Greenroads, the first rating system for sustainable road design and construction.Transportation Engineering and Road Research Alliance (TERRA). (2010). Greenroads.
Transportation Engineering and Road Research Alliance (TERRA)
core
Application of Internet in Road Traffic Engineering
Promet (Zagreb), 2012 The paper deals with the implementation of Internet in trafficengineering with the purpose of improving the professionaland scientific research development of the traffic system in theRepublic of Croatia.Fast growth of the world computer network ...
Ivan Dadić, Goran Kos
doaj +1 more source
"Analysis on top-down cracking resistance of rubber-plastic modified asphalt pavement"
Hecheng xiangjiao gongye, 2023 The properties of rubber-plastic modified asphalt mixture and SBS modified asphalt mixture were compared by splitting test, triaxial repeated load test and small beam bending test, and the stress variation law of the upper layer cracks on asphalt ...
HE Wei, LI Xin
doaj +1 more source