Results 21 to 30 of about 191,183 (260)

Pavement Engineering for Forest Roads: Development and Opportunities [PDF]

open access: yesCroatian Journal of Forest Engineering : Journal for Theory and Application of Forestry Engineering, 2020
Pavement is an essential component of roads as it carries the traffic and provides the required riding comfort. Considering that numerous forest roads are approaching their end of life, the critical issue is identifying the best rational pavement design methods to reengineer existing and build new pavement structures.
openaire   +4 more sources

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi   +9 more
wiley   +1 more source

A Framework of Integrated Sustainability and Value Engineering Concepts for Roads Projects [PDF]

open access: yesPort Said Engineering Research Journal
This research addressed the critical intersection of sustainability and road maintenance, "Major Arterial System," explicitly focusing on applying Value Engineering (VE) principles. In the face of mounting challenges posed by urbanization, climate change,
Sara Gabr   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Fly ash for sustainable roads: A comprehensive review on mechanisms and performance optimization

open access: yesJournal of Road Engineering
Fly ash (FA), a major solid waste from coal-fired industries, represents a critical pathway for the green disposal of bulk solid waste and the low-carbon construction of transportation infrastructure, holding significant strategic importance.
Yingxin Hui   +6 more
doaj   +1 more source

"Analysis on top-down cracking resistance of rubber-plastic modified asphalt pavement"

open access: yesHecheng xiangjiao gongye, 2023
The properties of rubber-plastic modified asphalt mixture and SBS modified asphalt mixture were compared by splitting test, triaxial repeated load test and small beam bending test, and the stress variation law of the upper layer cracks on asphalt ...
HE Wei, LI Xin
doaj   +1 more source

Engineering Tissues and Organs: The Road to the Clinic [PDF]

open access: yesCell, 2020
With recent advances in both gene editing and stem cell biology, the promise of cellular therapies is now closer than ever. Clinical trials for the application of chimeric antigen receptor T cells has driven an enormous investment into the development of such cellular products and learnings from these emboldening investors and engaging regulators ...
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Geotechnical Problems Of The Foundation Of Road Embankments By The Bridge Structures

open access: yesStudia Geotechnica et Mechanica, 2019
This work presents the geotechnical problems occurring in the interaction area between road embankments and the bridge structures in case a subsoil characterised by complex and complicated geological and engineering conditions. These significant problems
Batog Andrzej, Stilger-Szydło Elżbieta
doaj   +1 more source

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