Results 41 to 50 of about 4,462,462 (332)

The Leeds Advanced Driving Simulator: Three Years In Operation [PDF]

open access: yes, 1996
The Leeds Advanced Driving Simulator (LADS) at the University of Leeds is a medium cost fixed-base simulator and its development has been funded by the Science and Engineering Research Council (now EPSRC). It has been fully operational since mid-1993 for
Blana, E.
core   +1 more source

The Standardization Method and Application of the BIM Model for Interchanges

open access: yesApplied Sciences, 2022
Research on the standardization of interchange BIM components is required to encourage the use of BIM technology in interchange and quicken the development and improvement of relevant standards and specifications.
Yiyang Zhai   +5 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Geotechnical Problems Of The Foundation Of Road Embankments By The Bridge Structures

open access: yesStudia Geotechnica et Mechanica, 2019
This work presents the geotechnical problems occurring in the interaction area between road embankments and the bridge structures in case a subsoil characterised by complex and complicated geological and engineering conditions. These significant problems
Batog Andrzej, Stilger-Szydło Elżbieta
doaj   +1 more source

Review of current practices in recording road traffic incident data: with specific reference to spatial analysis and road policing policy [PDF]

open access: yes, 2003
Road safety involves three major components: the road system, the human factor and the vehicle element. These three elements are inter-linked through geo-referenced traffic events and provide the basis for road safety analyses and attempts to reduce ...
Anderson, Tessa
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Road landscape and engineering system Kyiv-Odesa: functioning, current geochemical state, problems of rational use

open access: yesВісник Харківського національного університету імені В.Н. Каразіна. Серія Геологія. Географія. Екологія
Formulation of the problem. The Kyiv-Odesa road landscape engineering system, one of the most powerful within Ukraine, is an optimal model for detailed studies of such status.
Hrigoriy Denysyk   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

On-stack replacement, distilled [PDF]

open access: yes, 2018
On-stack replacement (OSR) is essential technology for adaptive optimization, allowing changes to code actively executing in a managed runtime. The engineering aspects of OSR are well-known among VM architects, with several implementations available to ...
Bhandari Abhilash   +14 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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