Results 51 to 60 of about 231,296 (310)

Application of Road Engineering NSPM Action Programs on Sub-National Roads in Indonesia [PDF]

open access: yes, 2019
In Indonesia, the norm, the standard, the guidelines, and the manual regarding road engineering for sub-national roads are known as road engineering NSPM.
Sutandi, Anastasia Caroline; Parahyangan Catholic University Faculty of Engineering Civil Engineering Department Ciumbuleuit 94 Bandung 40141 Indonesia   +1 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Road MAPs to engineer host microbiomes

open access: yesCurrent Opinion in Microbiology, 2018
Microbiomes contribute directly or indirectly to host health and fitness. Thus far, investigations into these emergent traits, referred to here as microbiome-associated phenotypes (MAPs), have been primarily qualitative and taxonomy-driven rather than quantitative and trait-based.
Oyserman, Ben O.   +2 more
openaire   +2 more sources

Concrete Overlays [PDF]

open access: yes, 2011
This 2-page fact sheet provides information about concrete overlays, including their benefits and implementation.Transportation Engineering and Road Research Alliance (TERRA). (2011). Concrete Overlays.
Transportation Engineering and Road Research Alliance (TERRA)
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Pervious Concrete [PDF]

open access: yes, 2008
This 2-page fact sheet provides information about pervious concrete and its implementation in Minnesota.Transportation Engineering and Road Research Alliance (TERRA). (2008). Pervious Concrete.
Transportation Engineering and Road Research Alliance (TERRA)
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Performance analysis and prediction of asphalt pavement containing municipal solid waste incineration bottom ash aggregate based on MEPDG

open access: yesScientific Reports
Municipal solid waste incinerator (MSWI) bottom ash (BA) is the main product of municipal solid waste after being burned. MSWI bottom ash aggregate (BAA) which is made from processed BA can be used in road engineering due to its strength and gradation ...
Yu Sun   +5 more
doaj   +1 more source

Transportation Engineering and Road Research Alliance Strategic Plan FY 2014-FY 2016 (July 1, 2013 - June 30, 2016) [PDF]

open access: yes, 2013
Table of Contents: Strategic Planning Background (p. 1); TERRA Strategic Advantage and Value (p. 1); Environmental Scan (p. 2); TERRA Strategy (p. 3); Strategic Directions (pp. 3-5); Performance Measures (pp.
Transportation Engineering and Road Research Alliance (TERRA)
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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